I think that this will do well, but I'm not sure how good of a movie it will end up being. Family Guy has been VERY hit-or-miss in its recent run. If the quality is on the level of American Dad, though, I will DEFINITELY enjoy it.
Ted scored a very impressive $54.4 million from 3,239 locations. That bests the first Hangover movie's $44.98 million for highest debut ever for an original R-rated comedy. Among all R-rated movies it ranks eighth all-time, and it ranks third among comedies behind The Hangover Part II and Sex and the City.
Ted's success is due primarily to the strength of its broadly-appealing, completely original premise: what's not to like about a foul-mouthed, pot-smoking teddy bear hanging out with Mark Wahlberg? It didn't hurt that this felt like a logical transition to the big screen for Family Guy creator Seth MacFarlane, and previews maintained the general humor of that show while clearly bringing something new to the table.
It's also worth pointing out the importance of a great release date. Originally, Ted was scheduled for July 13, which was sandwiched directly in between The Amazing Spider-Man and The Dark Knight Rises. When G.I. Joe: Retaliation was bumped to next March, Universal immediately moved Ted up two weeks to June 29. As a result, Ted came out at a time when animated movies had ruled the box office for three-straight weeks, and when two R-rated comedies (The Dictator and That's My Boy) had already failed to deliver this Summer. This turned out to be the perfect time for a raunchy crowd-pleasing comedy like Ted, and kudos to Universal for figuring this out.
According to Universal's exit polling, Ted's audience skewed male (56 percent) and younger (52 percent were 30 years of age and under). They awarded the movie a very good "A-" CinemaScore, which implies that strong word-of-mouth should help Ted play well for at least the next month or so.