R&B singer Beyonce prefaced a song and dance performance by declaring: 'Oprah Winfrey, because of you, women everywhere have graduated to a new level of understanding of what we are, who we are, and who we can be ... We can run the world!'
Next, Beyonce showed up in a tuxedo leotard and sang "Run the World (Girls)" with a stage full of backup dancers. Mouthed Oprah from the audience, where she was sitting with Cruise, "Oh my God!" Beyonce's performance was taped twice, and the audience stood up and cheered each time.