| Pos | Pos+ | Artist and Title | Days | Peak | Pts | Released |
| 1 | = | P!nk - F**kin' Perfect | 27 | 1(4) | 0.338 | 11/16/10 |
| 2 | = | Pitbull - Hey Baby (Drop It to the Floor) [feat. T-Pain... | 123 | 2 | 1.003 | 9/17/10 |
| 3 | = | Bruno Mars - Grenade | 116 | 1(27) | 2.285 | 10/5/10 |
| 4 | = | Wiz Khalifa - Black and Yellow | 39 | 3 | 0.716 | 12/21/10 |
| 5 | = | Far East Movement & Ryan Tedder - Rocketeer | 50 | 5 | 0.453 | 10/9/10 |
| 6 | = | Diddy - Dirty Money & Skylar Grey - Coming Home | 46 | 4 | 0.591 | 12/14/10 |
| 7 | = | Katy Perry - Firework | 106 | 1(22) | 2.495 | 8/24/10 |
| 8 | = | Enrique Iglesias - Tonight (I'm Lovin' You) [feat. Luda... | 68 | 4 | 0.905 | 1/30/11 |
| 9 | = | Britney Spears - Hold It Against Me | 19 | 1(10) | 0.532 | 1/11/11 |
| 10 | = | The Black Eyed Peas - The Time (Dirty Bit) | 60 | 3 | 1.210 | 11/30/10 |
| 11 | = | Avril Lavigne - What the Hell | 18 | 2 | 0.260 | 1/7/11 |
| 12 | = | Christina Perri - Jar of Hearts | 106 | 12 | 0.711 | 7/27/10 |
| 13 | = | Lil Wayne - 6 Foot 7 Foot (feat. Cory Gunz) | 44 | 1(5) | 0.737 | 12/16/10 |
| 14 | +1 | Ke$ha - We R Who We R | 96 | 1(15) | 2.218 | 10/22/10 |
| 15 | -1 | Usher - More | 39 | 14 | 0.250 | 3/30/10 |
| 16 | = | Waka Flocka Flame - No Hands (feat. Roscoe Dash & Wale) | 144 | 12 | 1.113 | 9/6/10 |
| 17 | +1 | Rihanna & Drake - What's My Name? | 74 | 3 | 1.279 | 11/16/10 |
| 18 | -1 | Jeremih & 50 Cent - Down On Me (feat. 50 Cent) | 81 | 17 | 0.420 | 9/28/10 |
| 19 | = | Taio Cruz & Travie McCoy - Higher (Bonus Track) | 25 | 19 | 0.159 | 12/21/10 |
| 20 | = | Edward Maya & Vika Jigulina - Stereo Love | 111 | 12 | 0.823 | 2/2/10 |
| 21 | +1 | Taylor Swift - Back to December | 93 | 21 | 0.517 | 10/25/10 |
| 22 | +1 | Cee Lo Green - F**k You | 134 | 6 | 1.102 | 9/14/10 |
| 23 | +1 | Aerosmith - I Don't Want to Miss a Thing | 2 | 23 | 0.128 | 6/23/98 |
| 24 | +5 | Nicki Minaj & Drake - Moment 4 Life | 32 | 24 | 0.194 | 11/22/10 |
| 25 | = | Bruno Mars - Just the Way You Are | 193 | 1(12) | 3.186 | 7/20/10 |
| 26 | +1 | Chris Brown - Yeah 3X | 96 | 12 | 0.620 | 10/25/10 |
| 27 | +1 | Jason Aldean - Don't You Wanna Stay (with Kelly Clarkso... | 87 | 18 | 0.413 | 11/2/10 |
| 28 | -2 | Flo Rida - Who Dat Girl (feat. Akon) | 60 | 22 | 0.311 | 11/24/10 |
| 29 | -8 | The Script - Breakeven (Falling to Pieces) | 70 | 21 | 0.480 | 9/6/08 |
| 30 | +3 | Taio Cruz - Dynamite | 25 | 8 | 0.229 | 12/21/10 |
| 31 | -1 | Train - Marry Me | 59 | 24 | 0.329 | 10/26/09 |
| 32 | = | P!nk - Raise Your Glass | 114 | 3 | 1.788 | 10/6/10 |
| 33 | +3 | Trey Songz - Bottoms Up (feat. Nicki Minaj) | 137 | 5 | 1.720 | 9/14/10 |
| 34 | +1 | Kenny Chesney - Somewhere With You | 88 | 31 | 0.440 | 9/28/10 |
| 35 | +6 | Far East Movement, The Cataracs & Dev - Like a G6 | 179 | 1(16) | 2.782 | 10/9/10 |
| 36 | -5 | LMFAO - Party Rock Anthem (feat. Lauren Bennett & GoonR... | 4 | 29 | 0.024 | 1/25/11 |
| 37 | = | Keri Hilson - Pretty Girl Rock | 38 | 28 | 0.184 | 12/21/10 |
| 38 | +2 | Nelly - Just a Dream | 166 | 2 | 2.613 | 8/17/10 |
| 39 | +11 | P!nk - F**kin' Perfect | 21 | 35 | 0.115 | 12/14/10 |
| 40 | -6 | Lupe Fiasco - The Show Goes On | 39 | 18 | 0.242 | 10/25/10 |
| 41 | +4 | OneRepublic - Secrets | 219 | 16 | 1.382 | 11/17/09 |
| 42 | -3 | Rihanna - Only Girl (In the World) | 52 | 12 | 0.439 | 11/16/10 |
| 43 | = | Thompson Square - Are You Gonna Kiss Me or Not | 46 | 39 | 0.278 | 8/3/10 |
| 44 | -2 | Plain White T's - Rhythm of Love | 51 | 34 | 0.221 | 12/7/10 |
| 45 | +1 | Usher - DJ Got Us Fallin' In Love (feat. Pitbull) | 200 | 2 | 2.546 | 6/25/10 |
| 46 | -2 | The Lonely Island - I Just Had Sex (feat. Akon) | 41 | 7 | 0.279 | 12/19/10 |
| 47 | -9 | The Script - For the First Time | 11 | 21 | 0.069 | 1/18/11 |
| 48 | = | Troop 41 - Do the John Wall | 4 | 48 | 0.018 | 1/18/11 |
| 49 | -2 | Adele - Rolling In the Deep | 35 | 33 | 0.172 | 11/30/10 |
| 50 | -1 | Florence + The Machine - Dog Days Are Over | 158 | 3 | 0.877 | 7/5/09 |
| 51 | +1 | The Band Perry - If I Die Young | 108 | 14 | 0.703 | 10/12/10 |
| 52 | +1 | Dev & The Cataracs - Bass Down Low (feat. The Cataracs) | 38 | 41 | 0.164 | 12/7/10 |
| 53 | -2 | Tim McGraw - Felt Good On My Lips | 59 | 41 | 0.251 | 11/30/10 |
| 54 | +3 | Willow - Whip My Hair | 96 | 2 | 0.870 | 10/26/10 |
| 55 | +3 | Wiz Khalifa - Black and Yellow | 36 | 53 | 0.122 | 12/21/10 |
| 56 | +11 | Rihanna - S&M | 16 | 25 | 0.140 | 11/16/10 |
| 57 | +3 | Sugarland - Stuck Like Glue | 93 | 9 | 0.567 | 10/19/10 |
| 58 | +1 | Zac Brown Band - Colder Weather | 9 | 58 | 0.066 | 9/20/10 |
| 59 | -4 | David Guetta & Rihanna - Who's That Chick? (feat. Rihan... | 29 | 33 | 0.172 | 11/22/10 |
| 60 | -6 | Lil Wayne & Drake - Right Above It | 72 | 28 | 0.344 | 11/16/10 |
| 61 | +36 | Justin Bieber - Never Say Never | 2 | 61 | 0.010 | 1/25/11 |
| 62 | +6 | Cee Lo Green - Forget You | 85 | 17 | 0.396 | 9/14/10 |
| 63 | -2 | Billy Currington - Let Me Down Easy | 43 | 58 | 0.233 | 9/21/10 |
| 64 | -2 | Mumford & Sons - Little Lion Man | 175 | 38 | 0.738 | 2/16/10 |
| 65 | -2 | Neon Trees - Animal | 240 | 12 | 1.434 | 3/16/10 |
| 66 | -1 | Blake Shelton - Who Are You When I'm Not Looking | 84 | 50 | 0.341 | 8/6/10 |
| 67 | -3 | Mike Posner - Please Don't Go | 120 | 12 | 0.894 | 8/10/10 |
| 68 | +1 | Bruno Mars - Marry You | 70 | 37 | 0.254 | 10/5/10 |
| 69 | +1 | Kanye West - All of the Lights | 20 | 57 | 0.125 | 11/22/10 |
| 70 | +1 | The Black Eyed Peas - I Gotta Feeling | 237 | 31 | 0.870 | 6/9/09 |
| 71 | +3 | Enrique Iglesias - Tonight (I'm F**kin' You) [feat. Lud... | 68 | 13 | 0.357 | 11/22/10 |
| 72 | -16 | Rise Against - Help Is On the Way | 4 | 43 | 0.017 | 1/25/11 |
| 73 | = | Eminem - Love the Way You Lie (feat. Rihanna) | 223 | 1(33) | 3.238 | 6/21/10 |
| 74 | -2 | Linkin Park - Waiting for the End | 48 | 62 | 0.316 | 9/14/10 |
| 75 | = | Flo Rida - Club Can't Handle Me (feat. David Guetta) [F... | 210 | 5 | 1.992 | 6/28/10 |
| 76 | = | Katy Perry - Teenage Dream | 190 | 1(16) | 2.601 | 7/23/10 |
| 77 | +4 | Jerrod Niemann - What Do You Want | 22 | 75 | 0.212 | 7/13/10 |
| 78 | -12 | The Script - The Man Who Can't Be Moved | 41 | 64 | 0.271 | 9/6/08 |
| 79 | = | Sara Evans - A Little Bit Stronger | 45 | 48 | 0.314 | 9/14/10 |
| 80 | +4 | Train - Hey, Soul Sister | 228 | 14 | 1.177 | 8/7/09 |
| 81 | -1 | Kanye West & Jay-Z - H•A•M | 17 | 2 | 0.168 | 1/11/11 |
| 82 | = | Lady Antebellum - Need You Now | 97 | 38 | 0.445 | 1/26/10 |
| 83 | +3 | Mann - Buzzin' | 5 | 79 | 0.078 | 10/25/10 |
| 84 | +1 | Dr. Dre - Kush (feat. Snoop Dogg & Akon) | 72 | 12 | 0.344 | 11/18/10 |
| 85 | +7 | Enrique Iglesias - I Like It (feat. Pitbull) | 240 | 3 | 2.489 | 5/3/10 |
| 86 | +5 | Taylor Swift - Mine | 96 | 16 | 0.436 | 10/25/10 |
| 87 | +2 | P!nk - Raise Your Glass | 96 | 39 | 0.350 | 10/6/10 |
| 88 | -1 | Eminem - Not Afraid | 228 | 5 | 1.816 | 6/21/10 |
| 89 | +6 | Cali Swag District - Teach Me How to Dougie | 42 | 56 | 0.151 | 4/6/10 |
| 90 | -2 | Jason Aldean - My Kinda Party | 87 | 33 | 0.338 | 11/2/10 |
| 91 | -14 | Aerosmith - Dream On (Live) | 2 | 77 | 0.010 | 11/25/01 |
| 92 | +2 | Eminem - No Love (feat. Lil Wayne) | 165 | 8 | 0.867 | 6/21/10 |
| 93 | = | Yolanda Be Cool & Dcup - We No Speak Americano | 142 | 16 | 0.774 | 7/20/10 |
| 94 | -4 | Mumford & Sons - The Cave | 7 | 86 | 0.209 | 2/16/10 |
| 95 | +1 | Sara Bareilles - King of Anything | 144 | 16 | 0.577 | 9/7/10 |
| 96 | +4 | Justin Bieber & Ludacris - Baby | 142 | 27 | 0.727 | 3/23/10 |
| 97 | +6 | Ke$ha - Tik Tok | 150 | 28 | 0.722 | 1/4/09 |
| 98 | = | Fabolous - You Be Killin Em | 5 | 92 | 0.100 | 8/31/10 |
| 99 | +3 | Rick Ross - Aston Martin Music (feat. Drake & Chrisette... | 97 | 32 | 0.387 | 7/20/10 |
| 100 | +4 | Chris Brown - Yeah 3X | 7 | 97 | 0.133 | 10/25/10 |
| 101 | -2 | David Guetta - Memories | 47 | 72 | 0.307 | 3/26/10 |
| 102 | -24 | Optimo Aka Ken Green, Man Hit By Ice Cream Truck - Im G... | 2 | 73 | 0.011 | 8/7/10 |
| 104 | +17 | Ke$ha - Blow | -- | 104 | 0.049 | 11/19/10 |
| 113 | +28 | Amos Lee - Windows Are Rolled Down | -- | 113 | 0.007 | 1/21/11 |
| 114 | +28 | Sunny Sweeney - From a Table Away | -- | 114 | 0.009 | 1/18/11 |
| 143 | +50 | Your Favorite Martian - My Balls | -- | 143 | 0.004 | 12/24/10 |
| 148 | +9 | Travis Porter - Make It Rain | -- | 148 | 0.056 | 12/2/10 |
| 171 | +23 | P!nk - Raise Your Glass | -- | 171 | 0.015 | 11/16/10 |
| 175 | +33 | Mann & 50 Cent - Buzzin (Remix) [feat. 50 Cent] | -- | 175 | 0.024 | 12/21/10 |
| 237 | +82 | Cupid - Cupid Shuffle | -- | 162 | 0.224 | 9/11/07 |
| 279 | +92 | Nicki Minaj & Drake - Moment 4 Life | -- | 279 | 0.011 | 11/22/10 |
| 330 | +174 | Phil Collins - In the Air Tonight | -- | 234 | 0.133 | 10/5/98 |
| 374 | +194 | John Mayer - Say | -- | 246 | 0.133 | 10/13/06 |
| 397 | +108 | Bridgit Mendler - This Is My Paradise | -- | 224 | 0.012 | 1/11/11 |
| 406 | NEW | Miss Lawrence - Closet Freak | -- | 406 | 0.001 | 1/28/11 |
| 473 | +120 | Ester Dean & Chris Brown - Drop It Low | -- | 328 | 0.105 | 9/29/09 |
| 492 | +139 | Sean Hayes - Powerful Stuff | -- | 302 | 0.013 | 3/16/10 |
| 570 | +143 | Mr. C - Cha Cha Slide (Original Live Platinum Band Mix) | -- | 322 | 0.091 | 9/18/00 |
| 718 | +180 | Jamey Johnson - In Color | -- | 277 | 0.090 | 8/5/08 |
