| Pos | Pos+ | Artist and Title | Days | Peak | Pts | Released |
| 1 | +1 | Ke$ha - We R Who We R | 28 | 1(15) | 0.860 | 10/22/10 |
| 2 | +1 | Katy Perry - Firework | 38 | 2 | 0.569 | 8/24/10 |
| 3 | -2 | Glee Cast - Forget You (Glee Cast Version) [feat. Gwyne... | 6 | 1(4) | 0.183 | 11/16/10 |
| 4 | = | P!nk - Raise Your Glass | 46 | 4 | 0.765 | 10/6/10 |
| 5 | = | Rihanna - Only Girl (In the World) | 70 | 1(8) | 1.584 | 9/13/10 |
| 6 | = | The Black Eyed Peas - The Time (Dirty Bit) | 14 | 2 | 0.285 | 11/9/10 |
| 7 | +4 | Rihanna & Drake - What's My Name? | 6 | 7 | 0.056 | 11/16/10 |
| 8 | = | Far East Movement, The Cataracs & Dev - Like a G6 | 111 | 1(16) | 2.146 | 10/9/10 |
| 9 | -2 | Cee Lo Green - F**k You | 66 | 6 | 0.586 | 9/14/10 |
| 10 | = | Nelly - Just a Dream | 98 | 2 | 1.967 | 8/17/10 |
| 11 | +1 | Bruno Mars - Grenade | 48 | 11 | 0.273 | 10/5/10 |
| 12 | -3 | Glee Cast - Singing In the Rain / Umbrella (feat. Gwyne... | 6 | 2 | 0.117 | 11/16/10 |
| 13 | = | Trey Songz - Bottoms Up (feat. Nicki Minaj) | 69 | 5 | 0.876 | 9/14/10 |
| 14 | = | Bruno Mars - Just the Way You Are | 125 | 1(12) | 2.459 | 7/20/10 |
| 15 | = | Taio Cruz - Dynamite | 172 | 1(6) | 3.162 | 6/1/10 |
| 16 | = | Willow - Whip My Hair | 28 | 2 | 0.422 | 10/26/10 |
| 17 | +2 | Usher - DJ Got Us Fallin' In Love (feat. Pitbull) | 132 | 2 | 2.072 | 6/25/10 |
| 18 | -1 | Dr. Dre - Kush (feat. Snoop Dogg & Akon) | 4 | 14 | 0.038 | 11/18/10 |
| 19 | +2 | Wiz Khalifa - Black and Yellow | 60 | 17 | 0.349 | 9/14/10 |
| 20 | -2 | Sugarland - Stuck Like Glue | 25 | 9 | 0.203 | 10/19/10 |
| 21 | -1 | Flo Rida - Club Can't Handle Me (feat. David Guetta) [F... | 142 | 5 | 1.633 | 6/28/10 |
| 22 | +1 | Mike Posner - Please Don't Go | 52 | 12 | 0.424 | 8/10/10 |
| 23 | -1 | OneRepublic - Secrets | 151 | 16 | 0.977 | 11/17/09 |
| 24 | +2 | Neon Trees - Animal | 172 | 12 | 1.047 | 3/16/10 |
| 25 | +2 | The Band Perry - If I Die Young | 40 | 14 | 0.280 | 10/12/10 |
| 26 | +2 | Katy Perry - Teenage Dream | 122 | 1(16) | 2.290 | 7/23/10 |
| 27 | -2 | Glee Cast - Teenage Dream (Glee Cast Version) | 14 | 1(4) | 0.267 | 11/9/10 |
| 28 | +1 | Waka Flocka Flame - No Hands (feat. Roscoe Dash & Wale) | 76 | 14 | 0.499 | 9/6/10 |
| 29 | -5 | Cee Lo Green - Forget You | 28 | 17 | 0.184 | 9/14/10 |
| 30 | = | The Ready Set - Love Like Woe | 119 | 14 | 0.699 | 6/14/10 |
| 31 | = | Yolanda Be Cool & Dcup - We No Speak Americano | 74 | 16 | 0.508 | 7/20/10 |
| 32 | +1 | Enrique Iglesias - I Like It (feat. Pitbull) | 172 | 3 | 2.234 | 5/3/10 |
| 33 | -1 | Pitbull - Hey Baby (Drop It to the Floor) [feat. T-Pain... | 55 | 16 | 0.340 | 9/17/10 |
| 34 | +2 | Sean Kingston - Letting Go (Dutty Love) [feat. Nicki Mi... | 111 | 14 | 0.680 | 8/3/10 |
| 35 | +6 | Florence + The Machine - Dog Days Are Over | 90 | 3 | 0.491 | 7/5/09 |
| 36 | +1 | Nicki Minaj - Right Thru Me | 54 | 35 | 0.216 | 9/24/10 |
| 37 | +3 | Eminem - Love the Way You Lie (feat. Rihanna) | 155 | 1(33) | 2.958 | 6/21/10 |
| 38 | -3 | Christina Perri - Jar of Hearts | 38 | 35 | 0.254 | 7/27/10 |
| 39 | +5 | Taylor Swift - Mine | 28 | 16 | 0.172 | 10/25/10 |
| 40 | -2 | Nelly & Keri Hilson - Liv Tonight | 6 | 31 | 0.032 | 11/16/10 |
| 41 | -7 | The Beatles - Here Comes the Sun | 6 | 18 | 0.039 | 9/26/69 |
| 42 | -3 | Zac Brown Band - As She's Walking Away (feat. Alan Jack... | 60 | 29 | 0.251 | 9/20/10 |
| 43 | = | Edward Maya & Vika Jigulina - Stereo Love | 43 | 43 | 0.266 | 2/2/10 |
| 44 | +4 | Lil Wayne & Drake - Right Above It | 4 | 44 | 0.019 | 11/16/10 |
| 45 | = | Tim McGraw - Felt Good On My Lips | 20 | 11 | 0.132 | 11/2/10 |
| 46 | +5 | Eminem - No Love (feat. Lil Wayne) | 97 | 8 | 0.560 | 6/21/10 |
| 47 | = | Michael Jackson - Hold My Hand (Duet with Akon) | 4 | 47 | 0.016 | 11/18/10 |
| 48 | +2 | Ke$ha - Take It Off | 123 | 6 | 1.240 | 1/4/09 |
| 49 | = | Kenny Chesney - Somewhere With You | 20 | 43 | 0.099 | 9/28/10 |
| 50 | -8 | The Beatles - Let It Be | 6 | 24 | 0.033 | 5/8/70 |
| 51 | +10 | Chris Brown - Yeah 3X | 28 | 12 | 0.154 | 10/26/10 |
| 52 | +2 | P!nk - Raise Your Glass | 28 | 52 | 0.114 | 10/6/10 |
| 53 | -7 | The Beatles - In My Life | 6 | 25 | 0.032 | 12/3/65 |
| 54 | +2 | Jesse McCartney - Shake | 49 | 47 | 0.197 | 9/21/10 |
| 55 | = | Mumford & Sons - Little Lion Man | 107 | 38 | 0.494 | 2/16/10 |
| 56 | +11 | Taylor Swift - Back to December | 25 | 31 | 0.100 | 10/25/10 |
| 57 | +3 | Jeremih & 50 Cent - Down On Me (feat. 50 Cent) | 13 | 33 | 0.099 | 9/28/10 |
| 58 | -1 | Kanye West - Runaway (feat. Pusha T) | 50 | 2 | 0.371 | 10/4/10 |
| 59 | -7 | The Black Eyed Peas - I Gotta Feeling | 169 | 31 | 0.632 | 6/9/09 |
| 60 | -2 | Jason Aldean - My Kinda Party | 19 | 33 | 0.083 | 11/2/10 |
| 61 | +2 | Plain White T's - Rhythm of Love | 94 | 46 | 0.332 | 8/10/10 |
| 62 | -9 | Rihanna - S&M | 6 | 25 | 0.034 | 11/16/10 |
| 63 | -1 | Sara Bareilles - King of Anything | 76 | 16 | 0.355 | 9/7/10 |
| 64 | -5 | The Beatles - Come Together | 6 | 34 | 0.027 | 9/26/69 |
| 65 | +1 | Usher - Hot Tottie (feat. Jay-Z) | 90 | 17 | 0.480 | 8/24/10 |
| 66 | +5 | Rick Ross - Aston Martin Music (feat. Drake & Chrisette... | 40 | 32 | 0.196 | 7/20/10 |
| 67 | -2 | Jason Aldean - Don't You Wanna Stay (with Kelly Clarkso... | 20 | 18 | 0.097 | 11/2/10 |
| 68 | -4 | The Beatles - Blackbird | 6 | 33 | 0.027 | 11/22/68 |
| 69 | +1 | Katy Perry - California Gurls (feat. Snoop Dogg) | 170 | 1(29) | 2.630 | 5/7/10 |
| 70 | +2 | will.i.am & Nicki Minaj - Check It Out | 76 | 25 | 0.394 | 9/3/10 |
| 71 | -2 | Eric Church - Smoke a Little Smoke | 55 | 55 | 0.241 | 3/24/09 |
| 72 | -4 | Flo Rida - Turn Around (5,4,3,2,1) | 6 | 64 | 0.021 | 11/16/10 |
| 73 | +3 | B.o.B - Magic (feat. Rivers Cuomo) | 159 | 6 | 1.364 | 4/27/10 |
| 74 | = | Lupe Fiasco - The Show Goes On | 13 | 18 | 0.070 | 11/9/10 |
| 75 | +2 | Rihanna - Only Girl (In the World) | 4 | 75 | 0.016 | 11/16/10 |
| 76 | +3 | Eminem - Not Afraid | 166 | 5 | 1.598 | 6/21/10 |
| 77 | +6 | Cali Swag District - Teach Me How to Dougie | 151 | 28 | 0.675 | 4/6/10 |
| 78 | +7 | Chris Brown - Deuces (feat. Tyga & Kevin McCall) | 142 | 31 | 0.596 | 6/29/10 |
| 79 | -1 | Keri Hilson - Pretty Girl Rock | 6 | 78 | 0.045 | 10/12/10 |
| 80 | -7 | Ke$ha - Blow | 6 | 33 | 0.026 | 11/12/10 |
| 81 | = | Akon - Angel | 27 | 20 | 0.169 | 9/17/10 |
| 82 | -2 | Blake Shelton - Who Are You When I'm Not Looking | 17 | 67 | 0.107 | 8/6/10 |
| 83 | +15 | Train - Hey, Soul Sister | 160 | 14 | 0.931 | 8/7/09 |
| 84 | = | Mike Posner - Cooler Than Me (Single Mix) | 168 | 4 | 2.021 | 4/19/10 |
| 85 | -10 | The Beatles - Hey Jude | 6 | 47 | 0.022 | 4/19/73 |
| 86 | = | Kanye West, Jay-Z, Rick Ross, Nicki Minaj & Bon Iver - ... | 29 | 9 | 0.198 | 10/23/10 |
| 87 | -5 | Lady Antebellum - Hello World | 10 | 46 | 0.048 | 1/26/10 |
| 88 | +3 | David Guetta - Memories | 16 | 72 | 0.147 | 3/26/10 |
| 89 | +5 | Natasha Bedingfield - Strip Me | 39 | 53 | 0.160 | 9/21/10 |
| 90 | -2 | Keith Urban - Put You In a Song | 2 | 88 | 0.011 | 11/16/10 |
| 91 | +6 | Mariah Carey - All I Want for Christmas Is You (Origina... | 2 | 91 | 0.023 | 12/31/93 |
| 92 | -3 | Linkin Park - Waiting for the End | 18 | 63 | 0.143 | 9/14/10 |
| 93 | -3 | Lady Antebellum - Need You Now | 69 | 38 | 0.283 | 1/26/10 |
| 94 | +12 | Train - Marry Me | 1 | 94 | 0.072 | 10/26/09 |
| 95 | -8 | Miranda Lambert - Only Prettier | 29 | 57 | 0.249 | 9/29/09 |
| 96 | +25 | DJ Khaled - All I Do Is Win (feat. T-Pain, Ludacris, Sn... | 163 | 26 | 0.708 | 2/9/10 |
| 97 | +11 | Hannah Montana & Iyaz - Gonna Get This | 25 | 27 | 0.102 | 10/19/10 |
| 98 | +3 | Sara Evans - A Little Bit Stronger | 20 | 48 | 0.158 | 9/14/10 |
| 99 | -7 | Glee Cast - O Holy Night (Glee Cast Version) | 5 | 73 | 0.016 | 11/16/10 |
| 100 | +3 | Carrie Underwood - Mama's Song | 9 | 56 | 0.131 | 11/3/09 |
| 102 | -7 | The Beatles - Let It Be | 5 | 63 | 0.018 | 9/9/09 |
| 104 | -11 | Glee Cast - Start Me Up / Livin' On a Prayer (Glee Cast... | 13 | 2 | 0.118 | 11/9/10 |
| 105 | +2 | Rascal Flatts - Why Wait | -- | 105 | 0.009 | 11/16/10 |
| 112 | -13 | Carrie Underwood - There's a Place for Us | 5 | 32 | 0.022 | 11/16/10 |
| 117 | -21 | The Beatles - With a Little Help From My Friends | 5 | 55 | 0.018 | 6/1/67 |
| 132 | +9 | Jerrod Niemann - What Do You Want | -- | 132 | 0.065 | 7/13/10 |
| 179 | +18 | Troop 41 - Do the John Wall | -- | 179 | 0.055 | 2/23/09 |
| 180 | +24 | Lil Wayne & Drake - Gonorrhea | -- | 180 | 0.006 | 11/16/10 |
| 198 | NEW | Kanye West - All of the Lights | -- | 198 | 0.001 | 11/22/10 |
| 219 | NEW | Kanye West - Dark Fantasy | -- | 219 | 0.001 | 11/22/10 |
| 234 | +62 | Matt White - Love | 4 | 81 | 0.033 | 10/30/07 |
| 251 | +72 | Nick Cave & The Bad Seeds - O Children | -- | 251 | 0.002 | 12/31/03 |
| 264 | NEW | Ke$ha - Crazy Beautiful Life | -- | 264 | 0.001 | 11/19/10 |
| 288 | +103 | Rihanna & Drake - What's My Name? | -- | 288 | 0.003 | 11/16/10 |
| 303 | NEW | Ke$ha - The Harold Song | -- | 303 | 0.001 | 11/19/10 |
| 310 | NEW | Ke$ha - Grow a Pear | -- | 310 | 0.001 | 11/19/10 |
| 329 | +101 | Big Time Rush - Til I Forget About You | 4 | 51 | 0.050 | 10/11/10 |
| 333 | NEW | Kanye West, Kid Cudi & Raekwon - Gorgeous | -- | 333 | 0.001 | 11/22/10 |
| 336 | NEW | Diddy - Dirty Money & Skylar Grey - Coming Home (feat. ... | -- | 336 | 0.001 | 11/21/10 |
| 341 | +173 | Deadmau5 - Bad Selection | -- | 341 | 0.001 | 11/21/10 |
| 369 | +111 | Train - Drops of Jupiter | -- | 140 | 0.086 | 3/20/01 |
| 375 | NEW | Nicki Minaj & Drake - Moment 4 Life | -- | 375 | 0.001 | 11/22/10 |
| 376 | NEW | Nicki Minaj & Rihanna - Fly | -- | 376 | 0.001 | 11/22/10 |
| 405 | +117 | Cage the Elephant - Ain't No Rest for the Wicked | -- | 178 | 0.162 | 3/24/09 |
| 420 | NEW | Enrique Iglesias, Ludacris & DJ Frank E - Tonight (I'm ... | -- | 420 | 0.001 | 11/22/10 |
| 431 | +120 | Taylor Swift - Dear John | 11 | 7 | 0.107 | 10/25/10 |
| 465 | NEW | Nicki Minaj & Kanye West - Blazin' | -- | 465 | 0.001 | 11/22/10 |
| 466 | NEW | Kanye West & Pusha T - Runaway | -- | 466 | 0.001 | 11/22/10 |
| 495 | NEW | Ke$ha - C U Next Tuesday | -- | 495 | 0.001 | 11/19/10 |
| 520 | +156 | Drake - Over | 27 | 47 | 0.242 | 6/15/10 |
| 526 | NEW | Kanye West & Bon Iver - Lost In the World | -- | 526 | 0.000 | 11/22/10 |
| 529 | +193 | Oasis - Wonderwall | -- | 311 | 0.085 | 10/2/95 |
| 539 | NEW | Kanye West & John Legend - Blame Game | -- | 539 | 0.000 | 11/22/10 |
| 549 | NEW | Kanye West - Dark Fantasy | -- | 549 | 0.000 | 11/22/10 |
| 570 | +208 | Green Day - 21 Guns | -- | 152 | 0.146 | 5/15/09 |
| 595 | +153 | Diddy - Dirty Money - Hello Good Morning (Remix) [feat.... | 8 | 81 | 0.115 | 6/29/10 |
| 607 | NEW | Kanye West - All of the Lights | -- | 607 | 0.000 | 11/22/10 |
| 609 | +158 | Lil Wayne & T-Pain - Got Money | -- | 420 | 0.065 | 8/19/08 |
| 615 | +158 | Bruno Mars - Marry You | 4 | 61 | 0.027 | 10/5/10 |
| 647 | +301 | Lifehouse - You and Me | -- | 298 | 0.095 | 3/22/05 |
| 659 | +186 | Rock Mafia - The Big Bang | -- | 124 | 0.016 | 10/29/10 |
| 660 | NEW | Enrique Iglesias, Ludacris & DJ Frank E - Tonight (I'm ... | -- | 660 | 0.000 | 11/22/10 |
| 677 | NEW | Nicki Minaj - Blow Ya Mind | -- | 677 | 0.000 | 11/22/10 |
| 687 | +209 | Eminem - When I'm Gone | -- | 306 | 0.095 | 12/6/05 |
| 750 | +188 | Eminem - Without Me | -- | 382 | 0.075 | 5/26/02 |
