The song received universal critical acclaim, with critics calling it a catchy dance track and complimenting its anthemic nature.
"Rolling Stone named "Till the World Ends" as the third best song of 2011."
"Sam Lansky of PopCrush considered "Till the World Ends" the best pop song of 2011."
"Digital Spy also considered the track as the best song of 2011, naming it "Britney's best track since 'Toxic'" and commenting, "judging from its chart position, it's also her most underrated hit."
Pitchfork Media included the Femme Fatale Remix in their Top 100 Tracks of 2011 list, writing:
"'Till the World Ends' was already the best Britney single since 'Toxic', an ecstatic Euroclub floor-filler about wanting to dance until the world ends and other important matters. Then they added the Nicki Minaj verse.
American recording artist Kelly Clarkson covered the song during her Stronger Tour in 2012. During the Pink Friday Tour, Nicki Minaj included "Till the World Ends" as an interlude. Miranda Cosgrove covered the song in her Dancing Crazy Tour in a pop Medley. Electronicore band I See Stars covered the song on the compilation album Punk Goes Pop 4, which was released on November 21, 2011.
