In your opinion.

S&M. And Queen will STILL be in the lead for most #1s this millennium, ain't NOBODY taking her spot.

Sorry guys but... I don't think Madonna will have a #1 in the US again.

Maybe a posthumous #1.

Well that one of my wish!

Katy Perry - TGIF
Lady Gaga - Born This Way - 1st Single
Beyonce - 4th Studio Album - 1st Single + 2nd Single
Britney - 1st Single

I would love for this song to go #1, easily the standout track from Recovery!

Moment 4 Life if properly promoted
Tonight (I'm Loving You) I'm hoping
S&M depending on the video

Britney Spears - Hold It Against Me
Lady Gaga - Born This Way
Katy Perry - Last Friday Night (if it does get released as a single)

Maybe: Rihanna - S&M

Oh yeah, Space Bound and Moment 4 Life are deserving candidates as well, but I'm not sure if those will pull it off.

thats what IMO means

Cute imagination.

I dont need to imagine sis, shes coming in spring
She might be able to give Jason a final #1

I love her & Jason Derulo, but I must admit that "Coming Home" will definitely not be coming anywhere except the bubbling under chart. Not even Derulo, a king at single sales, can save that one.

And 'Boys & Girls' is her weakest single.
Actually.. let me be honest here, I only like about 5 songs from her album, and 4/5 are the main songs everyone knows from her ('Boys & Girls', 'Turn It Up', 'Gravity', 'Cry Me Out').. so those are good, but I don't think she's coming anywhere.

Especially with Rihanna, Katy, Britney, Avril, GaGa, and possibly Bey if she releases anything by spring?

You & your silly teenage dreams.

Sis no ones here for one opinion, the professionals disagree. and Boys & Girls holds 2 UK chart records, so if that is her weakest single then, I'll take it as a compliment
Billboard even named her as 'One to Watch', she is all set to launch her career in the states. Its confirmed she is releasing in spring, it doesn't matter who else is making music at that time, she is still coming

and i cant @ you not liking Coming Home, everyone loves it

Yes... in the UK.
When she comes to the US, then we can talk.
But for now, I'm gonna let the current, popular, most-popular-in-US faves we have sing their upcoming #1 smash hits for us.

Also, I don't know why I don't like it. Pixie has a great voice, and Jason did fine in it.. and it's impossible for him to not do fine cuz he's amazing at everything but still. I just didn't.

What the Hell
Hold It Against Me

I want S&M to go #1 but idk if it can.

Britney Spears - Hold It Agianst Me (#1 debut)
Avril Lavigne's What the Hell
Katy Perry & Rihanna Duet
Rihanna -S&M
Eminem's single from re-release
Bruno Mars next single
Lady GaGa's first 3 singles from BTW