| Pos | Pos+ | Artist and Title | Days | Peak | Pts | Released |
| 1 | = | Ke$ha - We R Who We R | 22 | 1(13) | 0.683 | 10/22/10 |
| 2 | = | Katy Perry - Firework | 32 | 2 | 0.422 | 8/24/10 |
| 3 | +1 | Rihanna & Drake - What's My Name? (feat. Drake) | 15 | 1(4) | 0.389 | 11/1/10 |
| 4 | -1 | Black Eyed Peas - The Time (Dirty Bit) | 8 | 2 | 0.166 | 11/9/10 |
| 5 | +1 | P!nk - Raise Your Glass | 40 | 5 | 0.636 | 10/6/10 |
| 6 | +1 | Rihanna - Only Girl (In the World) | 64 | 1(8) | 1.480 | 9/13/10 |
| 7 | +1 | Far East Movement, The Cataracs & Dev - Like a G6 | 105 | 1(16) | 2.046 | 10/9/10 |
| 8 | -3 | Glee Cast - Teenage Dream (Glee Cast Version) | 8 | 1(4) | 0.211 | 11/9/10 |
| 9 | = | Nelly - Just a Dream | 92 | 2 | 1.881 | 8/17/10 |
| 10 | = | Sugarland - Stuck Like Glue | 19 | 9 | 0.150 | 10/19/10 |
| 11 | +1 | Trey Songz - Bottoms Up (feat. Nicki Minaj) | 63 | 5 | 0.811 | 9/14/10 |
| 12 | -1 | Bruno Mars - Just the Way You Are | 119 | 1(12) | 2.399 | 7/20/10 |
| 13 | = | Taio Cruz - Dynamite | 166 | 1(6) | 3.110 | 6/1/10 |
| 14 | = | Willow - Whip My Hair | 22 | 2 | 0.367 | 10/26/10 |
| 15 | +5 | Bruno Mars - Grenade | 42 | 15 | 0.208 | 10/5/10 |
| 16 | +2 | The Band Perry - If I Die Young | 34 | 14 | 0.238 | 10/12/10 |
| 17 | -1 | Usher - DJ Got Us Fallin' In Love (feat. Pitbull) | 126 | 2 | 2.027 | 6/25/10 |
| 18 | -3 | Katy Perry - Teenage Dream | 116 | 1(16) | 2.251 | 7/23/10 |
| 19 | +4 | Wiz Khalifa - Black and Yellow | 54 | 17 | 0.301 | 9/14/10 |
| 20 | +1 | Mike Posner - Please Don't Go | 46 | 12 | 0.382 | 8/10/10 |
| 21 | +1 | OneRepublic - Secrets | 145 | 16 | 0.931 | 11/17/09 |
| 22 | -3 | Neon Trees - Animal | 166 | 12 | 1.007 | 3/16/10 |
| 23 | -6 | Flo Rida - Club Can't Handle Me (feat. David Guetta) [F... | 136 | 5 | 1.591 | 6/28/10 |
| 24 | +1 | Waka Flocka Flame - No Hands (feat. Roscoe Dash and Wal... | 70 | 14 | 0.461 | 9/6/10 |
| 25 | +1 | Cee Lo Green - F**k You | 60 | 12 | 0.496 | 9/14/10 |
| 26 | -2 | The Ready Set - Love Like Woe | 113 | 14 | 0.663 | 6/14/10 |
| 27 | +2 | Yolanda Be Cool & Dcup - We No Speak Americano | 68 | 16 | 0.474 | 7/20/10 |
| 28 | +5 | Pitbull - Hey Baby (Drop It to the Floor) [feat. T-Pain... | 49 | 16 | 0.307 | 9/17/10 |
| 29 | +1 | Zac Brown Band - As She's Walking Away (feat. Alan Jack... | 54 | 29 | 0.222 | 9/20/10 |
| 30 | -3 | Taylor Swift - Mine | 22 | 16 | 0.145 | 10/25/10 |
| 31 | +1 | Sean Kingston - Letting Go (Dutty Love) [feat. Nicki Mi... | 105 | 14 | 0.650 | 8/3/10 |
| 32 | +2 | Kid Cudi - Marijuana | 7 | 17 | 0.051 | 11/9/10 |
| 33 | -2 | Jason Aldean - Don't You Wanna Stay (with Kelly Clarkso... | 14 | 18 | 0.073 | 11/2/10 |
| 34 | +1 | Lil Wayne & Drake - Right Above It | 49 | 22 | 0.310 | 9/27/10 |
| 35 | +3 | Lupe Fiasco - The Show Goes On | 7 | 18 | 0.047 | 11/9/10 |
| 36 | -8 | Glee Cast - Start Me Up / Livin' On a Prayer (Glee Cast... | 8 | 2 | 0.099 | 11/9/10 |
| 37 | +4 | Nicki Minaj - Right Thru Me | 48 | 35 | 0.185 | 9/24/10 |
| 38 | +4 | Tim McGraw - Felt Good On My Lips | 14 | 11 | 0.104 | 11/2/10 |
| 39 | -2 | Eminem - Love the Way You Lie (feat. Rihanna) | 149 | 1(33) | 2.930 | 6/21/10 |
| 40 | +4 | Christina Perri - Jar of Hearts | 32 | 40 | 0.226 | 7/27/10 |
| 41 | -5 | Ke$ha - Take It Off | 117 | 6 | 1.217 | 1/4/09 |
| 42 | +4 | Jeremih & 50 Cent - Down On Me (feat. 50 Cent) | 7 | 33 | 0.076 | 9/28/10 |
| 43 | -4 | Enrique Iglesias - I Like It (feat. Pitbull) | 166 | 3 | 2.203 | 5/3/10 |
| 44 | +4 | Kanye West - Runaway (feat. Pusha T) | 44 | 2 | 0.348 | 10/4/10 |
| 45 | -5 | Taylor Swift - Back to December | 19 | 31 | 0.079 | 10/25/10 |
| 46 | +5 | Edward Maya & Vika Jigulina - Stereo Love | 37 | 46 | 0.241 | 2/2/10 |
| 47 | +5 | Eminem - No Love (feat. Lil Wayne) | 91 | 8 | 0.535 | 6/21/10 |
| 48 | -1 | will.i.am & Nicki Minaj - Check It Out | 70 | 25 | 0.375 | 9/3/10 |
| 49 | +8 | Mumford & Sons - Little Lion Man | 101 | 38 | 0.472 | 2/16/10 |
| 50 | -1 | Jason Aldean - My Kinda Party | 13 | 33 | 0.062 | 11/2/10 |
| 51 | -8 | Glee Cast - One Love (People Get Ready) [Glee Cast Vers... | 7 | 8 | 0.060 | 11/9/10 |
| 52 | +8 | Kenny Chesney - Somewhere With You | 14 | 48 | 0.073 | 9/28/10 |
| 53 | -3 | Ke$ha - Cannibal | 7 | 19 | 0.041 | 11/5/10 |
| 54 | -1 | Sara Bareilles - King of Anything | 70 | 16 | 0.335 | 9/7/10 |
| 55 | -10 | Glee Cast - Stop! In the Name of Love / Free Your Mind ... | 7 | 6 | 0.068 | 11/9/10 |
| 56 | +10 | Chris Brown - Yeah 3X | 22 | 12 | 0.131 | 10/26/10 |
| 57 | -1 | Usher - Hot Tottie (feat. Jay-Z) | 84 | 17 | 0.461 | 8/24/10 |
| 58 | -3 | Natasha Bedingfield - Strip Me | 33 | 53 | 0.144 | 9/21/10 |
| 59 | -5 | Lady Antebellum - Hello World | 4 | 46 | 0.031 | 1/26/10 |
| 60 | -1 | Jesse McCartney - Shake | 43 | 47 | 0.174 | 9/21/10 |
| 61 | +2 | Kid Cudi & Kanye West - Erase Me | 7 | 60 | 0.025 | 11/9/10 |
| 62 | +6 | Eric Church - Smoke a Little Smoke | 49 | 55 | 0.223 | 3/24/09 |
| 63 | -5 | B.o.B - Magic (feat. Rivers Cuomo) | 155 | 6 | 1.348 | 4/27/10 |
| 64 | +11 | Rick Ross - Aston Martin Music (feat. Drake & Chrisette... | 34 | 32 | 0.177 | 7/20/10 |
| 65 | +5 | Cee Lo Green - F**k You | 7 | 57 | 0.024 | 11/9/10 |
| 66 | -4 | P!nk - Raise Your Glass | 22 | 58 | 0.094 | 10/6/10 |
| 67 | = | Plain White T's - Rhythm of Love | 88 | 46 | 0.313 | 8/10/10 |
| 68 | XX | Miranda Lambert - The House That Built Me | 101 | 30 | 0.528 | 9/29/09 |
| 69 | +8 | Akon - Angel | 22 | 20 | 0.153 | 9/17/10 |
| 70 | +2 | Chris Brown - Deuces (feat. Tyga & Kevin McCall) | 139 | 31 | 0.582 | 6/29/10 |
| 71 | -10 | Katy Perry - California Gurls (feat. Snoop Dogg) | 166 | 1(29) | 2.613 | 5/7/10 |
| 72 | +12 | Kanye West, Jay-Z, Rick Ross, Nicki Minaj & Bon Iver - ... | 24 | 9 | 0.182 | 10/23/10 |
| 73 | = | Miranda Lambert - Only Prettier | 26 | 57 | 0.234 | 9/29/09 |
| 74 | -3 | The Black Eyed Peas & Justin Timberlake - Where Is the ... | 6 | 63 | 0.091 | 6/1/04 |
| 75 | +7 | Blake Shelton - Who Are You When I'm Not Looking | 11 | 67 | 0.090 | 8/6/10 |
| 76 | +4 | Keith Urban - Put You In a Song | 16 | 37 | 0.125 | 9/10/10 |
| 77 | +8 | Jason Derülo - What If | 7 | 60 | 0.023 | 11/9/10 |
| 78 | -9 | Lady Antebellum - Need You Now | 66 | 38 | 0.269 | 1/26/10 |
| 79 | +10 | David Guetta - Memories | 13 | 72 | 0.132 | 3/26/10 |
| 80 | -4 | Eminem - Not Afraid | 163 | 5 | 1.585 | 6/21/10 |
| 81 | = | Cali Swag District - Teach Me How to Dougie | 147 | 28 | 0.659 | 4/6/10 |
| 82 | -8 | Mike Posner - Cooler Than Me (Single Mix) | 166 | 4 | 2.006 | 4/19/10 |
| 83 | +3 | Cee Lo Green - Forget You | 22 | 72 | 0.141 | 9/14/10 |
| 84 | -6 | Maroon 5 - Misery | 55 | 13 | 0.250 | 9/21/10 |
| 85 | -6 | The Black Eyed Peas - I Gotta Feeling | 166 | 31 | 0.617 | 6/9/09 |
| 86 | +4 | Kid Cudi & Cee-Lo - Scott Mescudi vs. the World | 7 | 30 | 0.030 | 11/9/10 |
| 87 | +7 | DJ Khaled - All I Do Is Win (feat. T-Pain, Ludacris, Sn... | 162 | 26 | 0.696 | 2/9/10 |
| 88 | +3 | Little Big Town - Little White Church | 8 | 85 | 0.139 | 8/20/10 |
| 89 | +11 | Matt White - Love | 4 | 81 | 0.027 | 10/30/07 |
| 90 | -2 | Jay Sean - 2012 (It Ain't the End) [feat. Nicki Minaj] | 104 | 16 | 0.614 | 8/3/10 |
| 91 | +2 | George Strait - The Breath You Take | 6 | 63 | 0.159 | 8/11/09 |
| 92 | +6 | Ke$ha - Sleazy | 15 | 11 | 0.085 | 10/29/10 |
| 93 | +3 | David Guetta - Sexy Chick (feat. Akon) | 4 | 93 | 0.046 | 4/13/10 |
| 94 | +11 | Nicki Minaj - Roman's Revenge (feat. Eminem) | 14 | 17 | 0.071 | 10/31/10 |
| 95 | -3 | Kenny Chesney - The Boys of Fall | 67 | 10 | 0.446 | 8/3/10 |
| 96 | -9 | Selena Gomez & The Scene - A Year Without Rain | 45 | 19 | 0.183 | 9/21/10 |
| 97 | = | Rascal Flatts - Why Wait | 19 | 19 | 0.205 | 8/17/10 |
| 98 | +3 | Pitbull - Bon, Bon | 13 | 41 | 0.051 | 11/2/10 |
| 99 | +5 | Sara Evans - A Little Bit Stronger | 19 | 48 | 0.145 | 9/14/10 |
| 100 | -1 | Daughtry - September | 84 | 56 | 0.339 | 7/10/09 |
| 101 | +19 | The Script - For the First Time | -- | 101 | 0.013 | 11/9/10 |
| 102 | -7 | Jason Derülo - Ridin' Solo | 162 | 4 | 1.678 | 2/26/10 |
| 108 | +507 | Deadmau5 - Right This Second | -- | 108 | 0.003 | 11/14/10 |
| 113 | +9 | Luke Bryan - Someone Else Calling You Baby | -- | 113 | 0.030 | 10/2/09 |
| 114 | +11 | Train - Marry Me | -- | 114 | 0.060 | 10/26/09 |
| 127 | +14 | Third Eye Blind - Semi-Charmed Life | -- | 127 | 0.025 | 4/7/97 |
| 160 | +15 | Hootie & The Blowfish - Let Her Cry | -- | 160 | 0.013 | 5/25/04 |
| 171 | +23 | Chris Young - Voices | -- | 171 | 0.059 | 8/28/09 |
| 183 | +20 | Mariah Carey - All I Want for Christmas Is You | -- | 183 | 0.011 | 12/31/93 |
| 186 | +14 | Lil Jerk - Bottoms Up | -- | 186 | 0.004 | 10/1/10 |
| 189 | NEW | Ke$ha - Blow | -- | 189 | 0.001 | 11/12/10 |
| 197 | NEW | Sara Bareilles - Breathe Again | -- | 197 | 0.006 | 9/7/10 |
| 205 | +225 | Lee DeWyze - Sweet Serendipity | 7 | 51 | 0.038 | 10/15/10 |
| 215 | NEW | Carrie Underwood - There's a Place for Us | -- | 215 | 0.001 | 11/16/10 |
| 239 | NEW | Rihanna - S&M | -- | 239 | 0.001 | 11/16/10 |
| 270 | +70 | Wiz Khalifa - This Plane | -- | 216 | 0.072 | 11/24/09 |
| 276 | NEW | Josh Groban - Feels Like Home (Bonus Track) | -- | 276 | 0.001 | 11/12/10 |
| 292 | NEW | Mike Tompkins - Dynamite | -- | 292 | 0.001 | 9/17/10 |
| 302 | +403 | Duffy - Mercy | -- | 302 | 0.025 | 5/13/08 |
| 304 | +78 | Pitbull - I Know You Want Me (Calle Ocho) [More English... | -- | 236 | 0.128 | 2/24/09 |
| 313 | NEW | Black Eyed Peas - Do It Like This | -- | 313 | 0.001 | 11/16/10 |
| 356 | +110 | Chris Tomlin - Our God | -- | 356 | 0.004 | 3/5/10 |
| 381 | +153 | Kevjumba, Ryan Higa & Chester See - Shed a Tear | -- | 381 | 0.001 | 11/11/10 |
| 413 | NEW | Glee Cast - Forget You (Glee Cast Version) [feat. Gwyne... | -- | 413 | 0.001 | 11/16/10 |
| 424 | +551 | Jackie Evancho - Pie Jesu | -- | 213 | 0.007 | 10/19/10 |
| 429 | NEW | Rihanna & Drake - What's My Name? | -- | 429 | 0.001 | 11/16/10 |
| 437 | NEW | Flo Rida - Turn Around (5,4,3,2,1) | -- | 437 | 0.001 | 11/16/10 |
| 444 | +374 | Survivor - Eye of the Tiger | -- | 444 | 0.003 | 12/31/81 |
| 447 | +148 | JJ Heller - What Love Really Means | -- | 445 | 0.008 | 10/19/10 |
| 448 | NEW | Rihanna & Nicki Minaj - Raining Men | -- | 448 | 0.001 | 11/16/10 |
| 458 | NEW | P!nk - F**kin' Perfect | -- | 458 | 0.001 | 11/16/10 |
| 478 | +170 | Chris Brown - No B******t | -- | 223 | 0.014 | 6/29/10 |
| 496 | NEW | Glee Cast - Singing In the Rain / Umbrella (feat. Gwyne... | -- | 496 | 0.001 | 11/16/10 |
| 514 | +155 | Fantasia - I'm Doin' Me | -- | 295 | 0.009 | 8/20/10 |
| 559 | +140 | Deadmau5 - Sofi Needs a Ladder (Original Mix) | -- | 149 | 0.015 | 10/31/10 |
| 561 | NEW | A Day to Remember - You Be Tails, I'll Be Sonic | -- | 561 | 0.000 | 11/15/10 |
| 582 | NEW | P!nk - Heartbreak Down | -- | 582 | 0.000 | 11/16/10 |
| 612 | NEW | A Day to Remember - 2nd Sucks | -- | 612 | 0.000 | 11/15/10 |
| 620 | NEW | Rihanna - Fading | -- | 620 | 0.000 | 11/16/10 |
| 628 | NEW | Jamie Foxx - Fall for Your Type (feat. Drake) | -- | 628 | 0.000 | 11/12/10 |
| 660 | +216 | Sara Bareilles & Ingrid Michaelson - Winter Song | -- | 660 | 0.001 | 10/17/08 |
| 696 | +182 | OneRepublic & Sara Bareilles - Come Home | -- | 512 | 0.002 | 7/14/09 |
| 699 | NEW | Glee Cast - Nowadays / Hot Honey Rag (Glee Cast Version... | -- | 699 | 0.000 | 11/16/10 |
| 730 | +197 | Josh Groban - Believe | -- | 730 | 0.001 | 6/12/04 |
