| Pos | Pos+ | Artist and Title | Days | Peak | Released |
| 1 | = | Katy Perry - California Gurls (feat. Snoop Dogg) | 2 | 1(x2) | 5/7/10 |
| 2 | = | Usher - OMG (feat. will.i.am) | 2 | 2 | 3/30/10 |
| 3 | = | B.o.B - Airplanes (feat. Hayley Williams of Paramore) | 2 | 3 | 4/13/10 |
| 4 | = | Drake - Miss Me (feat. Lil Wayne) | 2 | 4 | 6/1/10 |
| 5 | = | Travie McCoy - Billionaire (feat. Bruno Mars) | 2 | 5 | 3/9/10 |
| 6 | = | Ke$ha - Your Love Is My Drug | 2 | 6 | 1/5/10 |
| 7 | = | Black Eyed Peas - Rock That Body | 2 | 7 | 6/9/09 |
| 8 | = | Lady GaGa - Alejandro | 2 | 8 | 11/23/09 |
| 9 | = | Eminem - Not Afraid | 2 | 9 | 5/3/10 |
| 10 | = | La Roux - Bulletproof | 2 | 10 | 9/22/09 |
| 11 | +2 | Taio Cruz - Dynamite | 2 | 11 | 6/1/10 |
| 12 | +2 | Mike Posner - Cooler Than Me (Single Mix) | 2 | 12 | 4/6/10 |
| 13 | +3 | 3OH!3 - My First Kiss (feat. Ke$ha) | 2 | 13 | 5/4/10 |
| 14 | +3 | Miley Cyrus - Can't Be Tamed | 2 | 14 | 5/18/10 |
| 15 | -4 | T.I. - Yeah Ya Know (Takers) | 2 | 11 | 6/1/10 |
| 16 | -1 | Drake - Find Your Love | 2 | 15 | 5/5/10 |
| 17 | +1 | Train - Hey, Soul Sister | 2 | 17 | 8/7/09 |
| 18 | -6 | T.I. - Got Your Back (feat. Keri Hilson) | 2 | 12 | 6/1/10 |
| 19 | +44 | Taio Cruz & Ludacris - Break Your Heart | 2 | 19 | 6/1/10 |
| 20 | -1 | Jay-Z - Young Forever (feat. Mr. Hudson) | 2 | 19 | 9/8/09 |
| 21 | -1 | Carrie Underwood - Undo It | 2 | 20 | 11/3/09 |
| 22 | = | Sean Kingston & Justin Bieber - Eenie Meenie | 2 | 22 | 3/23/10 |
| 23 | -2 | B.o.B - Nothin' On You (feat. Bruno Mars) | 2 | 21 | 12/15/09 |
| 24 | +1 | Jason Derülo - Ridin' Solo | 2 | 24 | 2/26/10 |
| 25 | -1 | Shontelle - Impossible | 2 | 24 | 2/9/10 |
| 26 | = | Timbaland - If We Ever Meet Again (feat. Katy Perry) | 2 | 26 | 12/8/09 |
| 27 | +5 | Justin Bieber & Ludacris - Baby | 2 | 27 | 3/23/10 |
| 28 | +1 | Lady Antebellum - Need You Now | 2 | 28 | 1/26/10 |
| 29 | -1 | Ke$ha - Tik Tok | 2 | 28 | 1/5/10 |
| 30 | = | Jaron and The Long Road to Love - Pray for You | 2 | 30 | 3/23/10 |
| 31 | +2 | Nickelback - This Afternoon | 2 | 31 | 11/18/08 |
| 32 | +3 | DJ Khaled - All I Do Is Win (feat. T-Pain, Ludacris, Snoop Dogg &... | 2 | 32 | 2/9/10 |
| 33 | -10 | Glee Cast - Good Vibrations (Glee Cast Version) | 2 | 23 | 6/11/10 |
| 34 | +3 | Miranda Lambert - The House That Built Me | 2 | 34 | 9/29/09 |
| 35 | +7 | Black Eyed Peas - I Gotta Feeling | 2 | 35 | 6/9/09 |
| 36 | +2 | Jason Derülo - In My Head | 2 | 36 | 12/8/09 |
| 37 | -6 | Jack Johnson - You and Your Heart | 2 | 31 | 6/1/10 |
| 38 | -11 | 3OH!3 - Déjŕ Vu | 2 | 27 | 6/1/10 |
| 39 | = | Kevin Rudolf - I Made It (Cash Money Heroes) [feat. Birdman, Jay ... | 2 | 39 | 2/23/10 |
| 40 | +3 | Ludacris & Nicki Minaj - My Chick Bad | 2 | 40 | 3/9/10 |
| 41 | +5 | Lady GaGa & Beyoncé - Telephone | 2 | 41 | 1/26/10 |
| 42 | +6 | The Script - Breakeven (Falling to Pieces) | 2 | 42 | 11/4/08 |
| 43 | +7 | Jerrod Niemann - Lover, Lover | 2 | 43 | 3/9/10 |
| 44 | +7 | Rihanna - Rude Boy | 2 | 44 | 11/23/09 |
| 45 | +8 | Travie McCoy - Billionaire (feat. Bruno Mars) | 2 | 45 | 3/9/10 |
| 46 | +3 | Drake - Over | 2 | 46 | 3/8/10 |
| 47 | +5 | B.o.B - Airplanes (feat. Hayley Williams of Paramore) | 2 | 47 | 4/13/10 |
| 48 | +6 | Michael Bublé - Haven't Met You Yet | 2 | 48 | 10/6/09 |
| 49 | +13 | Justin Bieber - Somebody to Love | 2 | 49 | 3/23/10 |
| 50 | -6 | Glee Cast - Poker Face (Glee Cast Version) [feat. Idina Menzel] | 2 | 44 | 5/21/10 |
| 51 | +4 | Lady GaGa - Bad Romance | 2 | 51 | 10/26/09 |
| 52 | -18 | Glee Cast - Another One Bites the Dust (Glee Cast Version) | 2 | 34 | 6/11/10 |
| 53 | +4 | Black Eyed Peas - Imma Be | 2 | 53 | 6/9/09 |
| 54 | +4 | Enrique Iglesias - I Like It (feat. Pitbull) | 2 | 54 | 5/3/10 |
| 55 | -14 | Lee DeWyze & Crystal Bowersox - Falling Slowly (American Idol Stu... | 2 | 41 | 5/11/10 |
| 56 | = | Jamie Foxx - Winner (feat. Justin Timberlake & T.I.) | 2 | 56 | 4/6/10 |
| 57 | -10 | Lee DeWyze - Hallelujah (American Idol Studio Version) | 2 | 47 | 5/18/10 |
| 58 | +2 | Billy Currington - Pretty Good At Drinkin' Beer | 2 | 58 | 6/1/10 |
| 59 | -19 | Lee DeWyze - Beautiful Day | 2 | 40 | 5/27/10 |
| 60 | -24 | Glee Cast - Tell Me Something Good (Glee Cast Version) | 2 | 36 | 6/11/10 |
| 61 | +9 | Diddy - Dirty Money - Hello Good Morning (feat. T.I.) | 2 | 61 | 3/30/10 |
| 62 | +2 | David Guetta & Chris Willis - Gettin' Over You (feat. Fergie & LM... | 2 | 62 | 4/13/10 |
| 63 | +5 | Luke Bryan - Rain Is a Good Thing | 2 | 63 | 10/6/09 |
| 64 | +2 | Lady Antebellum - American Honey | 2 | 64 | 1/26/10 |
| 65 | +4 | Uncle Kracker - Smile | 2 | 65 | 9/14/09 |
| 66 | -1 | Adam Lambert - Whataya Want from Me | 2 | 65 | 11/20/09 |
| 67 | -22 | Glee Cast - It's a Man's, Man's Man's World (Glee Cast Version) | 2 | 45 | 6/11/10 |
| 68 | -1 | Iyaz - Solo | 2 | 67 | 2/8/10 |
| 69 | +3 | Timbaland - Carry Out (feat. Justin Timberlake) | 2 | 69 | 12/8/09 |
| 70 | +9 | Brad Paisley - Water | 2 | 70 | 6/30/09 |
| 71 | -10 | Taio Cruz & Ke$ha - Dirty Picture | 2 | 61 | 6/1/10 |
| 72 | -1 | Colbie Caillat - I Never Told You | 2 | 71 | 8/25/09 |
| 73 | +11 | Owl City - Fireflies | 2 | 73 | 7/14/09 |
| 74 | -1 | OneRepublic - All the Right Moves | 2 | 73 | 11/17/09 |
| 75 | +3 | Lee Brice - Love Like Crazy | 2 | 75 | 2/2/10 |
| 76 | +7 | Lady GaGa - Poker Face | 2 | 76 | 10/28/08 |
| 77 | +5 | Ke$ha - Blah Blah Blah (feat. 3OH!3) | 2 | 77 | 1/5/10 |
| 78 | +3 | Alicia Keys - Un-thinkable (I'm Ready) | 2 | 78 | 11/27/09 |
| 79 | -2 | Cody Simpson - iYiYi (feat. Flo Rida) | 2 | 77 | 6/1/10 |
| 80 | +9 | V V Brown - Shark In the Water | 2 | 80 | 2/2/10 |
| 81 | -1 | Paramore - The Only Exception | 2 | 80 | 9/29/09 |
| 82 | +5 | Jay-Z - Empire State of Mind (feat. Alicia Keys) | 2 | 82 | 9/8/09 |
| 83 | -7 | 3OH!3 - Touchin On My | 2 | 76 | 5/18/10 |
| 84 | +2 | Lil Wayne & Eminem - Drop the World | 2 | 84 | 2/2/10 |
| 85 | +5 | Eminem - Not Afraid | 2 | 85 | 5/18/10 |
| 86 | +5 | Neon Trees - Animal | 2 | 86 | 3/16/10 |
| 87 | -2 | Young Jeezy - Lose My Mind (feat. Plies) | 2 | 85 | 3/30/10 |
| 88 | = | Muse - Uprising | 2 | 88 | 9/11/09 |
| 89 | +5 | Zac Brown Band - Free | 2 | 89 | 11/17/08 |
| 90 | -31 | Glee Cast - Loser (Glee Cast Version) | 2 | 59 | 6/11/10 |
| 91 | +5 | Miley Cyrus - Party In the U.S.A. | 2 | 91 | 8/11/09 |
| 92 | +1 | Lloyd Banks - Beamer, Benz, or Bentley (feat. Juelz Santana) | 2 | 92 | 2/8/10 |
| 93 | +4 | Lady GaGa & Colby O'Donis - Just Dance | 2 | 93 | 10/28/08 |
| 94 | +1 | Joe Nichols - Gimmie That Girl | 2 | 94 | 10/26/09 |
| 95 | +5 | Journey - Don't Stop Believin' | 2 | 95 | 11/14/88 |
| 96 | +9 | Beyoncé - Single Ladies (Put a Ring On It) | 1 | 96 | 11/18/08 |
| 97 | +2 | Selena Gomez & The Scene - Naturally | 2 | 97 | 9/29/09 |
| 98 | +4 | T.I. - I'm Back | 1 | 98 | 3/9/10 |
| 99 | +7 | Jay-Z - Young Forever (feat. Mr. Hudson) | 1 | 99 | 9/8/09 |
| 100 | -8 | Glee Cast - Jessie's Girl (Glee Cast Version) | 2 | 92 | 5/12/10 |
| 108 | NEW | Nicki Minaj - Your Love | -- | 108 | 6/1/10 |
| 290 | +74 | One eskimO - Kandi | -- | 290 | 12/22/09 |
| 463 | +234 | Countess Luann - Money Can't Buy You Class (Radio Edit) | -- | 463 | 5/25/10 |
| 473 | +134 | Robin Thicke - It's In the Mornin' (feat. Snoop Dogg) | -- | 473 | 12/15/09 |
| 568 | +203 | Big Time Rush - Big Time Rush | -- | 568 | 4/23/10 |
| 610 | NEW | Smashing Pumpkins - Bullet With Butterfly Wings | -- | 610 | 11/19/01 |
| 615 | +180 | Taio Cruz & Ludacris - Break Your Heart (Mixin Marc & Tony Svejda... | -- | 615 | 6/1/10 |
| 632 | NEW | T.I. - Got Your Back (feat. Keri Hilson) | -- | 632 | 6/1/10 |
| 636 | NEW | T.I. - Yeah Ya Know (Takers) | -- | 636 | 6/1/10 |
| 655 | +230 | 50 Cent - In da Club | -- | 655 | 2/6/03 |
| 699 | +264 | Big Time Rush - Any Kind of Guy | -- | 699 | 2/2/10 |
| 732 | +229 | Young MC - Bust a Move | -- | 732 | 12/31/88 |
