The blast was in a large park in the south-west of the city, where many people had gathered late on Sunday. Police told the BBC it appeared to be a suicide bomb.There is speculation that Christian families out for the Easter weekend may have been the target.
All the major hospitals in the area have been put on an emergency footing to deal with casualties, local media report. The explosion appears to have been at the main gate to the Gulshan-e-Iqbal park in an area where cars are usually left.