That is higher than any MCU movie other than the Avengers and Iron-Man movies, also higher than all X-Men movies, unadjusted of course (X3 did $45m back in 2006.)
This is likely going to be 20th Century Fox's biggest opener ever, unadjusted. (Fox's current highest opening weekend is Star Wars: Revenge of the Sith with $108m back in 2005)