45Secs doesn't seem like an era defining song, but I think it's more about Rihanna making a statement than it is about get a high charting song. It's most definitely her Secret.
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Those Bruno performances! Does Jizziano have a performance as good as those?
It's Mark's song, although Bruno is not a mere feature like ATRL likes to claim to dismiss his participation. It's partially Bruno's creation as well and the success of it was decisively because Bruno's name and image was attached to it and because of his live performances.