What do you mean? Like your appearence changes once you start having sex? No.
People do way too much on the whole virgin thing, it really doesn't change anything, it doesn't matter, it's not like your life will be different once you've had a dick in there henny.
If you're on the receiving end of the D, I suppose that change the way you walk and does impact the center of attention as well (if you have it a lot). But you aren't going to lose your virginity and look anew