DC were a girl band, but Gaga is a solo artist. And who says Gaga will get a second chance if this album doesn't sell much? That DC album sold over 2 million copies worldwide in the end - hardly a flop.
(Btw I like her songs and don't think she is a flop, but I'm just pointing out that your comparison is useless.)
The Fame is setting the charts on fire in Australia and New Zealand. Also, after she tours she'll have enough money to pay her 2nd album. She said in an interview that she won't give up the music business. In Gaga we trust.