Never affected me too closely thankfully.
My grandma died of Kidney Cancer, but she lived in Poland so I only saw her a few times. It didn't affect me badly like it did my mom.
I know a bunch of people from school that had one of their parents die from cancer, it's sad
And my best friends' mom found out two years ago that she had breast cancer. She got part of them removed and doesn't have it anymore thankfully.