When I was in tenth grade a girl that I used to be friends with did ecstasy during school and went all crazy causing her to get expelled and have to get counselling.
It was really crazy because it was just as lunch break was ending and half the school was watching her. Some of her friends were trying to calm her down but she was like crying and screaming and at one point she started rolling around on the floor (

).
Even as the bell rang everybody was still standing around, some of the teachers even came out and were watching from the second floor (where I was).
Thankfully the principal and vice-principal stepped in and got her to calm down. The entire school was talking about it for the rest of the week.
Edit: not too sure if it actually was ecstasy but it was some kind of drug... I don't really remember which one..