a really fat bitch, one comparable to a cow's size
damn, u actually stuck ur penis in that heffer?
2. heffer
1) A really conceited girl. A chick with a very nasty attitude.
2) An overweight chick.
Dat heffer better watch herself, or she'll get jumped! Daamnnn, look at dat huge ass heffer over there!
3. heffer
Street term for a half ounce of green.Also known just as heff too.
John:Hey man, you got a heffer free'd up?
James:Let me look in the stockade,yeah got 2 left.
John:35 a heff right?
James:Yup, you rollin' thru?
John:Of course, but you know that heffer won't last all night...