I don't like how Wolverine-centric the X-Men films are, and some of the casting in them kind of bothered me (like, I think Anna Paquin is cool and all, but I wanted sexy, badass southern belle Rogue). And where was Gambit in the first three? He was probably the second or third most popular X-Man of the '90s and they snubbed him till Origins, and then didn't even do him justice.

But I haven't seen very many of the other series so I'll vote for X-Men anyway. And Fantastic Four 'cause of the eye candy.