The celebrated fashion photographer - who has shot everyone from Kate Moss to the Duke and Duchess of Cambridge - believes his career has had such longevity because he has the ability to adapt and reinvent himself for every client, just like the Queen of Pop.
He admitted: 'Ultimately I made my range wider because I wanted to suit each publication that I worked for. Talk about reinvention - I'm like the Madonna of photography.'
Peruvian-born Mario experienced 'total poverty when he first moved to London, but soon realised he could make a living out of his passion for taking striking snapshots.
He also touched upon his good relationship with the British royal family, from his iconic portrait of the late Princess Diana to the engagement photos of Prince William and Duchess Catherine.
Prince William and Kate Middleton, engagement portrait by Testino,
Mario described it as 'a whole new realm of photography', which has been 'a gift to his career'.
I love his work with Madonna (The 1995 photoshoot is my most favourite ever (I've even bought a calendar from 1995 because I love that era so much )
His photoshoots are truly remarkable, i. e. Lady Di