I used Explorer, Mozilla & Chrome and I have to say that Chrome is definitely the best.
Mozilla is fine but after long usage when you have big history, cookies, temporary files and other ****, it starts getting unbearably slow, freezes, doesn't want to restart immediately because the Mozilla process is still running etc. It is also naturally slower than Chrome.
IE is crap, I only used when I have to download Firefox and/or Chrome for a new or re-installed computer. I use Chrome like 90 % of the time, it's the faster and more intuitive one for me; and I basically use Firefox only for proxy purposes.