Ignoring manicure as a single would be the biggest mistake this era. It's a radio smash waiting to happen. I actually foresee a 6-7 singles this era only because of lots of radio friendly songs in the album
I'm not a huge fan of "Manicure", but I could see it working as a 5th or 6th single after "Gypsy", "Sexxx Dreams" and "G.U.Y". I'm still not sold on "G.U.Y." working on radio though, I mean it's an incredible song, but it just doesn't have that radio sound to it. I see "Manicure" performing better than it.