He's had conflicts with Interscope (Madonna is part of the label now) in the past. The only reasonable reason why 50 Cent would be up in arms about it this time is if Madonna's first single is Girls Gone Wild.
Ugh I don't know what to think about Girls Gone Wild.
Madonnarama reported a collab between Benssai and M called Girls Gone Wild and that it's going to be a single.
Benassi denied it.
Madonnarama still insists it's a real song.
Apparently GIrls Gone Wild wasn't played at the listening party for executives, which suggests the song never existed.
50 Cent brings it up.
Now it's rumoured to be the album title.