I think it will happen. A lot of things that were really good happened to her in the past year, and she got a lot of praise from many people for an amazing job she did with those things. If a top 10 doesn't happen, it is what it is. The music is more important.
If even a heavily promoted Katy single fails to go top 10 it's gonna be difficult for Gaga. This post is entirely on-topic by the way, as it compares results from other main pop girl singles.
#13 Do What U Want
#76 G.U.Y.
N/A Anything Goes
N/A I Can't Give You Anything but Love
#95 Till It Happens To You
No shade, but judging from her latest releases I don't see it happening. Hopefully I'm wrong.
How clever of you to conveniently ignore the lead single of her last pop release (which went top 5) when the question is regarding her next lead single.
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Top 10 is highly likely with a proper release. Anything more is up to whether the song itself genuinely clicks with the public or not.
#13 Do What U Want
#76 G.U.Y.
N/A Anything Goes
N/A I Can't Give You Anything but Love
#95 Till It Happens To You
No shade, but judging from her latest releases I don't see it happening. Hopefully I'm wrong.
Of course you'd leave out her last actual lead single Applause that peaked at #4 but included some covers of jazz standards that are almost a century old and were not sent to radio to discredit her.
little monsters, but I don't see it happening 
I'm honestly 100% sure it's going Top 10. Lemme bookmark this when it debuts there 
Hopefully I'm wrong.