| Pos | Pos+ | Artist and Title | Days | Peak | Pts | Released |
| 1 | = | Bruno Mars - Grenade | 79 | 1(4) | 1.098 | 10/5/10 |
| 2 | +1 | Katy Perry - Firework | 69 | 1(22) | 1.586 | 8/24/10 |
| 3 | -1 | Lil Wayne - 6 Foot 7 Foot (feat. Cory Gunz) | 7 | 1(5) | 0.233 | 12/16/10 |
| 4 | +1 | Ke$ha - We R Who We R | 59 | 1(15) | 1.517 | 10/22/10 |
| 5 | -1 | The Black Eyed Peas - The Time (Dirty Bit) | 23 | 3 | 0.488 | 11/30/10 |
| 6 | = | Rihanna & Drake - What's My Name? | 37 | 3 | 0.710 | 11/16/10 |
| 7 | +3 | Enrique Iglesias - Tonight (I'm Lovin' You) [feat. Luda... | 31 | 7 | 0.197 | 1/11/11 |
| 8 | -1 | The Lonely Island - I Just Had Sex (feat. Akon) | 4 | 7 | 0.056 | 12/19/10 |
| 9 | -1 | Diddy - Dirty Money & Skylar Grey - Coming Home | 9 | 8 | 0.097 | 12/14/10 |
| 10 | -1 | P!nk - Raise Your Glass | 77 | 3 | 1.362 | 10/6/10 |
| 11 | = | Trey Songz - Bottoms Up (feat. Nicki Minaj) | 100 | 5 | 1.319 | 9/14/10 |
| 12 | = | Bruno Mars - Just the Way You Are | 156 | 1(12) | 2.867 | 7/20/10 |
| 13 | = | Nelly - Just a Dream | 129 | 2 | 2.301 | 8/17/10 |
| 14 | = | Edward Maya & Vika Jigulina - Stereo Love | 74 | 12 | 0.501 | 2/2/10 |
| 15 | = | Rihanna - Only Girl (In the World) | 15 | 12 | 0.146 | 11/16/10 |
| 16 | = | Waka Flocka Flame - No Hands (feat. Roscoe Dash & Wale) | 107 | 14 | 0.753 | 9/6/10 |
| 17 | +50 | Wiz Khalifa - Black and Yellow | 2 | 17 | 0.013 | 12/21/10 |
| 18 | = | Far East Movement, The Cataracs & Dev - Like a G6 | 142 | 1(16) | 2.486 | 10/9/10 |
| 19 | -2 | Taio Cruz - Dynamite | 203 | 1(6) | 3.414 | 6/1/10 |
| 20 | -1 | Chris Brown - Yeah 3X | 59 | 12 | 0.342 | 10/25/10 |
| 21 | +6 | Taio Cruz & Travie McCoy - Higher (feat. Travie McCoy) | 2 | 21 | 0.016 | 12/20/10 |
| 22 | -2 | Usher - DJ Got Us Fallin' In Love (feat. Pitbull) | 163 | 2 | 2.299 | 6/25/10 |
| 23 | -2 | Mike Posner - Please Don't Go | 83 | 12 | 0.666 | 8/10/10 |
| 24 | -2 | Pitbull - Hey Baby (Drop It to the Floor) [feat. T-Pain... | 86 | 16 | 0.532 | 9/17/10 |
| 25 | -2 | OneRepublic - Secrets | 182 | 16 | 1.173 | 11/17/09 |
| 26 | -2 | Cee Lo Green - F**k You | 97 | 6 | 0.837 | 9/14/10 |
| 27 | +2 | Taylor Swift - Back to December | 56 | 27 | 0.266 | 10/25/10 |
| 28 | -2 | Willow - Whip My Hair | 59 | 2 | 0.649 | 10/26/10 |
| 29 | -1 | Christina Perri - Jar of Hearts | 69 | 27 | 0.414 | 7/27/10 |
| 30 | +1 | 3OH!3 - Hit It Again | 2 | 30 | 0.013 | 12/21/10 |
| 31 | -6 | The Band Perry - If I Die Young | 71 | 14 | 0.497 | 10/12/10 |
| 32 | = | Neon Trees - Animal | 203 | 12 | 1.236 | 3/16/10 |
| 33 | = | Eminem - No Love (feat. Lil Wayne) | 128 | 8 | 0.708 | 6/21/10 |
| 34 | = | Far East Movement & Ryan Tedder - Rocketeer | 13 | 33 | 0.101 | 10/9/10 |
| 35 | = | Mariah Carey - All I Want for Christmas Is You (Origina... | 33 | 18 | 0.214 | 12/31/93 |
| 36 | +2 | Sugarland - Stuck Like Glue | 56 | 9 | 0.377 | 10/19/10 |
| 37 | -7 | Michael Jackson - Hold My Hand (Duet with Akon) | 9 | 21 | 0.060 | 12/14/10 |
| 38 | -2 | Flo Rida - Club Can't Handle Me (feat. David Guetta) [F... | 173 | 5 | 1.810 | 6/28/10 |
| 39 | -2 | Kenny Chesney - Somewhere With You | 51 | 31 | 0.252 | 9/28/10 |
| 40 | -1 | Florence + The Machine - Dog Days Are Over | 121 | 3 | 0.717 | 7/5/09 |
| 41 | = | Katy Perry - Teenage Dream | 153 | 1(16) | 2.442 | 7/23/10 |
| 42 | -2 | The Ready Set - Love Like Woe | 150 | 14 | 0.858 | 6/14/10 |
| 43 | -1 | Jason Aldean - Don't You Wanna Stay (with Kelly Clarkso... | 50 | 18 | 0.213 | 11/2/10 |
| 44 | -1 | Lil Wayne & Drake - Right Above It | 35 | 39 | 0.158 | 11/16/10 |
| 45 | -1 | Dr. Dre - Kush (feat. Snoop Dogg & Akon) | 35 | 12 | 0.218 | 11/18/10 |
| 46 | +6 | Eminem - Love the Way You Lie (feat. Rihanna) | 186 | 1(33) | 3.085 | 6/21/10 |
| 47 | +4 | Tim McGraw - Felt Good On My Lips | 22 | 47 | 0.087 | 11/30/10 |
| 48 | -1 | Jeremih & 50 Cent - Down On Me (feat. 50 Cent) | 44 | 33 | 0.215 | 9/28/10 |
| 49 | -1 | Enrique Iglesias - Tonight (I'm F**kin' You) [feat. Lud... | 31 | 13 | 0.236 | 1/11/11 |
| 50 | +7 | Brad Paisley - This Is Country Music | 2 | 50 | 0.009 | 12/21/10 |
| 51 | -5 | B.o.B - I Am the Champion (2010/2011 Championship Footb... | 2 | 46 | 0.009 | 12/21/10 |
| 52 | +3 | Eminem - Not Afraid | 191 | 5 | 1.688 | 6/21/10 |
| 53 | +6 | Taylor Swift - Mine | 59 | 16 | 0.285 | 10/25/10 |
| 54 | = | Sara Bareilles - King of Anything | 107 | 16 | 0.454 | 9/7/10 |
| 55 | -2 | Sean Kingston - Party All Night (Sleep All Day) | 2 | 53 | 0.009 | 12/21/10 |
| 56 | -11 | T.I. - That's All She Wrote (feat. Eminem) | 17 | 4 | 0.226 | 12/7/10 |
| 57 | +3 | Nicki Minaj - Right Thru Me | 28 | 34 | 0.118 | 11/22/10 |
| 58 | -2 | Kanye West, Prynce Cy Hi & Teyana Taylor - Christmas In... | 2 | 56 | 0.011 | 12/17/10 |
| 59 | -1 | Yolanda Be Cool & Dcup - We No Speak Americano | 105 | 16 | 0.649 | 7/20/10 |
| 60 | +1 | Jason Aldean - My Kinda Party | 50 | 33 | 0.195 | 11/2/10 |
| 61 | -11 | Hollywood Undead - Hear Me Now | 2 | 50 | 0.009 | 12/21/10 |
| 62 | = | Blake Shelton - Who Are You When I'm Not Looking | 47 | 58 | 0.205 | 8/6/10 |
| 63 | = | P!nk - Raise Your Glass | 59 | 39 | 0.230 | 10/6/10 |
| 64 | +1 | Train - Hey, Soul Sister | 191 | 14 | 1.046 | 8/7/09 |
| 65 | +3 | Mumford & Sons - Little Lion Man | 138 | 38 | 0.603 | 2/16/10 |
| 66 | +3 | Plain White T's - Rhythm of Love | 14 | 54 | 0.053 | 12/7/10 |
| 67 | -1 | Flo Rida - Who Dat Girl (feat. Akon) | 23 | 22 | 0.104 | 11/24/10 |
| 68 | +2 | Enrique Iglesias - I Like It (feat. Pitbull) | 203 | 3 | 2.360 | 5/3/10 |
| 69 | -5 | Victorious Cast - Freak the Freak Out (feat. Victoria J... | 25 | 13 | 0.125 | 11/22/10 |
| 70 | +17 | Katy Perry - California Gurls (feat. Snoop Dogg) | 11 | 52 | 0.101 | 8/24/10 |
| 71 | = | B.o.B - Magic (feat. Rivers Cuomo) | 173 | 6 | 1.434 | 4/27/10 |
| 72 | +79 | Keri Hilson - Pretty Girl Rock | 1 | 72 | 0.005 | 12/21/10 |
| 73 | +2 | Usher - More | 5 | 73 | 0.031 | 3/30/10 |
| 74 | +10 | Jamie Foxx - Fall for Your Type (feat. Drake) | 2 | 74 | 0.006 | 12/17/10 |
| 75 | +1 | Glee Cast - Last Christmas (Glee Cast Version) | 16 | 16 | 0.105 | 11/16/10 |
| 76 | -4 | Birdman & Lil Wayne - Fire Flame (feat. Lil Wayne) | 22 | 54 | 0.086 | 11/22/10 |
| 77 | +3 | Train - Marry Me | 28 | 58 | 0.160 | 10/26/09 |
| 78 | +1 | The Black Eyed Peas - I Gotta Feeling | 200 | 31 | 0.730 | 6/9/09 |
| 79 | +2 | Ke$ha - Take It Off | 148 | 6 | 1.329 | 1/4/09 |
| 80 | -6 | Bruno Mars - Marry You | 33 | 37 | 0.138 | 10/5/10 |
| 81 | -4 | Rick Ross - Aston Martin Music (feat. Drake & Chrisette... | 70 | 32 | 0.291 | 7/20/10 |
| 82 | = | Akon - Angel | 58 | 20 | 0.293 | 9/17/10 |
| 83 | +6 | Trans-Siberian Orchestra - Christmas / Sarajevo 12/24 (... | 26 | 63 | 0.098 | 10/14/96 |
| 84 | -11 | Billy Currington - Let Me Down Easy | 13 | 72 | 0.125 | 9/21/10 |
| 85 | +5 | Coldplay - Christmas Lights | 22 | 3 | 0.200 | 12/1/10 |
| 86 | +7 | Mike Posner - Cooler Than Me (Single Mix) | 179 | 4 | 2.091 | 4/19/10 |
| 87 | -2 | Thompson Square - Are You Gonna Kiss Me or Not | 10 | 80 | 0.135 | 8/3/10 |
| 88 | +3 | Glee Cast - Baby, It's Cold Outside (Glee Cast Version) | 19 | 14 | 0.125 | 11/16/10 |
| 89 | +8 | Train - Shake Up Christmas (Coke Xmas Anthem) | 2 | 89 | 0.024 | 11/1/10 |
| 90 | -4 | David Guetta - Memories | 42 | 72 | 0.230 | 3/26/10 |
| 91 | -3 | Lil Wayne & Cory Gunz - 6 Foot 7 Foot (feat. Cory Gunz) | 2 | 88 | 0.016 | 12/16/10 |
| 92 | -9 | Daft Punk - Derezzed | 6 | 66 | 0.035 | 12/7/10 |
| 93 | +2 | Zac Brown Band - As She's Walking Away (feat. Alan Jack... | 91 | 29 | 0.353 | 9/20/10 |
| 94 | -16 | Dev & The Cataracs - Bass Down Low (feat. The Cataracs) | 16 | 41 | 0.058 | 12/7/10 |
| 95 | -1 | Kanye West & Pusha T - Runaway | 30 | 52 | 0.100 | 11/22/10 |
| 96 | +3 | Cee Lo Green - Forget You | 55 | 17 | 0.283 | 9/14/10 |
| 97 | +5 | Justin Bieber & Ludacris - Baby | 126 | 27 | 0.632 | 3/23/10 |
| 98 | +2 | Troop 41 - Do The John Wall | 3 | 95 | 0.010 | 11/19/10 |
| 99 | +4 | Trans-Siberian Orchestra - Christmas Canon | 9 | 91 | 0.067 | 9/14/98 |
| 100 | -2 | Cali Swag District - Teach Me How to Dougie | 8 | 84 | 0.043 | 4/6/10 |
| 101 | +20 | Jimmy Fallon - Drunk On Christmas (feat. John Rich) [Li... | -- | 101 | 0.004 | 12/21/10 |
| 113 | -21 | P!nk - F**kin' Perfect | 8 | 44 | 0.035 | 12/14/10 |
| 123 | +50 | Meredith Brooks - Bitch | -- | 123 | 0.004 | 4/24/97 |
| 124 | -28 | Coldplay - Fix You | 2 | 82 | 0.023 | 6/7/05 |
| 131 | +54 | Wild Cherry - Play That Funky Music | -- | 131 | 0.006 | 12/31/75 |
| 143 | +46 | MC Hammer - U Can't Touch This | -- | 110 | 0.054 | 9/9/96 |
| 150 | +45 | The Verve Pipe - The Freshmen | -- | 150 | 0.003 | 3/25/96 |
| 162 | +57 | Grace Potter & The Nocturnals - Paris (Ooh La La) | -- | 127 | 0.032 | 6/8/10 |
| 174 | NEW | Wiz Khalifa - Black and Yellow | -- | 174 | 0.002 | 12/21/10 |
| 194 | +17 | Dexy's Midnight Runners & Kevin Rowland - Come On Eilee... | -- | 194 | 0.002 | 4/3/07 |
| 197 | +8 | Fugees - Killing Me Softly With His Song | -- | 197 | 0.008 | 4/1/03 |
| 198 | +54 | Matchbox Twenty - 3 AM | -- | 198 | 0.002 | 9/28/07 |
| 199 | +36 | Crazy Town - Butterfly | -- | 199 | 0.002 | 10/25/99 |
| 204 | +257 | Coolio - Gangsta's Paradise | -- | 142 | 0.027 | 3/15/05 |
| 223 | +211 | Sixpence None the Richer - Kiss Me | -- | 223 | 0.002 | 11/21/97 |
| 226 | +72 | Wiz Khalifa - Make It Hot | -- | 226 | 0.004 | 7/28/08 |
| 227 | +61 | Eartha Kitt - Santa Baby | -- | 185 | 0.024 | 1/1/06 |
| 229 | +374 | Nitty Gritty Dirt Band - Fishin' In the Dark | -- | 229 | 0.001 | 12/31/86 |
| 240 | +67 | Adam Sandler - The Chanukah Song | -- | 109 | 0.034 | 2/12/96 |
| 273 | +486 | T-Pain featuring Yung Joc - Buy U a Drank (Shawty Snapp... | -- | 273 | 0.001 | 6/5/07 |
| 285 | +359 | Manfred Mann's Earth Band - Blinded By the Light | -- | 285 | 0.001 | 12/31/95 |
| 291 | +332 | Percy Sledge - When a Man Loves a Woman | -- | 291 | 0.009 | 12/31/65 |
| 308 | +281 | Nickelback - How You Remind Me | -- | 308 | 0.019 | 9/10/01 |
| 330 | +224 | Big & Rich - Save a Horse (Ride a Cowboy) | -- | 330 | 0.049 | 4/20/04 |
| 353 | +154 | Run-DMC - Christmas In Hollis | -- | 289 | 0.013 | 12/31/86 |
| 378 | +435 | Gary Wright - Dream Weaver | -- | 378 | 0.001 | 12/31/74 |
| 383 | +313 | Marc Cohn - Walking In Memphis | -- | 184 | 0.026 | 6/20/06 |
| 395 | +108 | Pat Benatar - Hit Me With Your Best Shot | -- | 395 | 0.012 | 6/7/05 |
| 404 | +160 | Destiny's Child - Jumpin', Jumpin' | -- | 333 | 0.015 | 7/27/99 |
| 406 | +104 | Thin Lizzy - The Boys Are Back in Town | -- | 406 | 0.001 | 12/31/75 |
| 419 | +321 | Joe Walsh - Life's Been Good | -- | 236 | 0.022 | 12/31/77 |
| 433 | +523 | Foreigner - Juke Box Hero | -- | 433 | 0.001 | 7/8/08 |
| 438 | +294 | Brandon Heath - Give Me Your Eyes | -- | 438 | 0.018 | 10/1/97 |
| 447 | +466 | Jackie Evancho - O Holy Night | -- | 248 | 0.022 | 11/16/10 |
| 452 | +533 | Digital Underground - The Humpty Dance | -- | 244 | 0.016 | 8/22/06 |
| 459 | +169 | Keith Urban - You'll Think Of Me | -- | 337 | 0.019 | 10/4/02 |
| 461 | +554 | Rehab - Sittin At a Bar | -- | 461 | 0.001 | 10/23/00 |
| 511 | NEW | Lecrae - Overdose | -- | 511 | 0.000 | 12/22/10 |
| 515 | NEW | Dixie Chicks - Cowboy Take Me Away | -- | 515 | 0.000 | 10/26/10 |
| 522 | +322 | Stone Sour - Through Glass | -- | 508 | 0.012 | 2/6/07 |
| 540 | +386 | Skid Row - I Remember You | -- | 540 | 0.001 | 12/31/89 |
| 541 | NEW | Luke Bryan - All My Friends Say | -- | 541 | 0.000 | 8/14/07 |
| 548 | +414 | Tenth Avenue North - By Your Side | -- | 548 | 0.005 | 5/20/08 |
| 566 | +254 | Bee Gees - Stayin' Alive | -- | 154 | 0.057 | 9/17/07 |
| 592 | +425 | Naughty By Nature - O.P.P. | -- | 249 | 0.017 | 9/2/91 |
| 594 | NEW | Sixpence None the Richer - There She Goes | -- | 594 | 0.000 | 11/21/97 |
| 612 | +176 | B.o.B - I Am the Champion (2010/2011 Championship Footb... | -- | 612 | 0.001 | 12/21/10 |
| 622 | NEW | Avenged Sevenfold - Almost Easy | -- | 622 | 0.000 | 10/26/07 |
| 646 | +166 | Alan Jackson - Chattahoochee | -- | 646 | 0.001 | 8/7/07 |
| 667 | +342 | Buffalo Springfield - For What It's Worth | -- | 346 | 0.011 | 5/24/05 |
| 669 | NEW | Twisted Sister - We're Not Gonna Take It | -- | 669 | 0.000 | 6/26/07 |
| 670 | +226 | Mann & 50 Cent - Buzzin (Remix) [feat. 50 Cent] | -- | 670 | 0.001 | 12/21/10 |
| 694 | NEW | The Doobie Brothers - Listen to the Music | -- | 694 | 0.000 | 2/6/07 |
| 700 | +191 | Bing Crosby - White Christmas | -- | 451 | 0.011 | 12/31/94 |
| 747 | +195 | Toby Keith - Should've Been a Cowboy | -- | 747 | 0.001 | 4/20/93 |