The Hollywood Reporter have had an interview with Kevin Feige, wherein it is confirmed, that Spider-Man will first appear in Captain America: Civil War.
“Holland will report immediately to the set of the currently shooting Captain America: Civil War, which Marvel has scheduled for a May 6, 2016, release and in which the newest Spider-Man will make his first onscreen appearance,” The Reporter’s Gregg Kilday wrote.
Tom Holland were recently cast as the teenage web-slinger.
Source: ComicBook.com