| Pos | Pos+ | Artist and Title | Days | Peak | Pts | Released |
| 1 | = | Bruno Mars - Grenade | 93 | 1(18) | 1.598 | 10/5/10 |
| 2 | = | Katy Perry - Firework | 83 | 1(22) | 1.976 | 8/24/10 |
| 3 | = | The Black Eyed Peas - The Time (Dirty Bit) | 37 | 3 | 0.785 | 11/30/10 |
| 4 | = | Ke$ha - We R Who We R | 73 | 1(15) | 1.855 | 10/22/10 |
| 5 | = | Enrique Iglesias - Tonight (I'm Lovin' You) [feat. Luda... | 45 | 4 | 0.465 | 1/11/11 |
| 6 | +1 | Wiz Khalifa - Black and Yellow | 16 | 6 | 0.245 | 12/21/10 |
| 7 | +1 | Lil Wayne - 6 Foot 7 Foot (feat. Cory Gunz) | 21 | 1(5) | 0.420 | 12/16/10 |
| 8 | -2 | Rihanna & Drake - What's My Name? | 51 | 3 | 1.005 | 11/16/10 |
| 9 | = | P!nk - Raise Your Glass | 91 | 3 | 1.584 | 10/6/10 |
| 10 | = | Trey Songz - Bottoms Up (feat. Nicki Minaj) | 114 | 5 | 1.545 | 9/14/10 |
| 11 | = | Diddy - Dirty Money & Skylar Grey - Coming Home | 23 | 8 | 0.237 | 12/14/10 |
| 12 | = | Waka Flocka Flame - No Hands (feat. Roscoe Dash & Wale) | 121 | 12 | 0.889 | 9/6/10 |
| 13 | +2 | Edward Maya & Vika Jigulina - Stereo Love | 88 | 12 | 0.609 | 2/2/10 |
| 14 | +2 | Rihanna - Only Girl (In the World) | 29 | 12 | 0.285 | 11/16/10 |
| 15 | +16 | Taio Cruz - Dynamite | 2 | 15 | 0.026 | 12/21/10 |
| 16 | -2 | Far East Movement, The Cataracs & Dev - Like a G6 | 156 | 1(16) | 2.630 | 10/9/10 |
| 17 | = | Bruno Mars - Just the Way You Are | 170 | 1(12) | 3.012 | 7/20/10 |
| 18 | -5 | Nelly - Just a Dream | 143 | 2 | 2.471 | 8/17/10 |
| 19 | = | Chris Brown - Yeah 3X | 73 | 12 | 0.444 | 10/25/10 |
| 20 | -2 | Cee Lo Green - F**k You | 111 | 6 | 0.926 | 9/14/10 |
| 21 | = | Pitbull - Hey Baby (Drop It to the Floor) [feat. T-Pain... | 100 | 16 | 0.624 | 9/17/10 |
| 22 | +2 | Far East Movement & Ryan Tedder - Rocketeer | 27 | 22 | 0.180 | 10/9/10 |
| 23 | -1 | Christina Perri - Jar of Hearts | 83 | 22 | 0.494 | 7/27/10 |
| 24 | -4 | Mike Posner - Please Don't Go | 97 | 12 | 0.775 | 8/10/10 |
| 25 | +1 | The Lonely Island - I Just Had Sex (feat. Akon) | 18 | 7 | 0.153 | 12/19/10 |
| 26 | +2 | OneRepublic - Secrets | 196 | 16 | 1.264 | 11/17/09 |
| 27 | -4 | Usher - DJ Got Us Fallin' In Love (feat. Pitbull) | 177 | 2 | 2.413 | 6/25/10 |
| 28 | -3 | Taylor Swift - Back to December | 70 | 21 | 0.363 | 10/25/10 |
| 29 | = | Lil Wayne & Drake - Right Above It | 49 | 28 | 0.241 | 11/16/10 |
| 30 | -3 | Willow - Whip My Hair | 73 | 2 | 0.755 | 10/26/10 |
| 31 | -1 | The Band Perry - If I Die Young | 85 | 14 | 0.589 | 10/12/10 |
| 32 | +4 | Flo Rida - Who Dat Girl (feat. Akon) | 37 | 22 | 0.162 | 11/24/10 |
| 33 | -1 | Neon Trees - Animal | 217 | 12 | 1.328 | 3/16/10 |
| 34 | +3 | Kenny Chesney - Somewhere With You | 65 | 31 | 0.316 | 9/28/10 |
| 35 | = | Plain White T's - Rhythm of Love | 28 | 35 | 0.109 | 12/7/10 |
| 36 | -2 | Sugarland - Stuck Like Glue | 70 | 9 | 0.462 | 10/19/10 |
| 37 | +1 | Jason Aldean - Don't You Wanna Stay (with Kelly Clarkso... | 64 | 18 | 0.275 | 11/2/10 |
| 38 | -5 | Flo Rida - Club Can't Handle Me (feat. David Guetta) [F... | 187 | 5 | 1.895 | 6/28/10 |
| 39 | +3 | Jeremih & 50 Cent - Down On Me (feat. 50 Cent) | 58 | 33 | 0.269 | 9/28/10 |
| 40 | = | Florence + The Machine - Dog Days Are Over | 135 | 3 | 0.778 | 7/5/09 |
| 41 | = | Tim McGraw - Felt Good On My Lips | 36 | 41 | 0.149 | 11/30/10 |
| 42 | -3 | Eminem - No Love (feat. Lil Wayne) | 142 | 8 | 0.784 | 6/21/10 |
| 43 | +2 | Keri Hilson - Pretty Girl Rock | 15 | 28 | 0.075 | 12/21/10 |
| 44 | +14 | Usher - More | 16 | 44 | 0.072 | 3/30/10 |
| 45 | -2 | The Ready Set - Love Like Woe | 164 | 14 | 0.940 | 6/14/10 |
| 46 | +1 | Eminem - Love the Way You Lie (feat. Rihanna) | 200 | 1(33) | 3.153 | 6/21/10 |
| 47 | +46 | Taio Cruz & Travie McCoy - Higher (Bonus Track) | 2 | 47 | 0.007 | 12/21/10 |
| 48 | -4 | Katy Perry - California Gurls (feat. Snoop Dogg) | 25 | 32 | 0.172 | 8/24/10 |
| 49 | +2 | Dr. Dre - Kush (feat. Snoop Dogg & Akon) | 49 | 12 | 0.270 | 11/18/10 |
| 50 | -1 | Jason Aldean - My Kinda Party | 64 | 33 | 0.258 | 11/2/10 |
| 51 | -1 | Mumford & Sons - Little Lion Man | 152 | 38 | 0.652 | 2/16/10 |
| 52 | -6 | Taylor Swift - Mine | 73 | 16 | 0.364 | 10/25/10 |
| 53 | = | Blake Shelton - Who Are You When I'm Not Looking | 61 | 53 | 0.255 | 8/6/10 |
| 54 | -6 | B.o.B - Magic (feat. Rivers Cuomo) | 187 | 6 | 1.500 | 4/27/10 |
| 55 | +1 | Sara Bareilles - King of Anything | 121 | 16 | 0.506 | 9/7/10 |
| 56 | +3 | Thompson Square - Are You Gonna Kiss Me or Not | 23 | 56 | 0.175 | 8/3/10 |
| 57 | -3 | Yolanda Be Cool & Dcup - We No Speak Americano | 119 | 16 | 0.701 | 7/20/10 |
| 58 | +8 | Train - Marry Me | 36 | 58 | 0.197 | 10/26/09 |
| 59 | +6 | Nicki Minaj & Drake - Moment 4 Life | 9 | 59 | 0.092 | 11/22/10 |
| 60 | +45 | Gerry Rafferty - Baker Street | 1 | 60 | 0.006 | 12/31/77 |
| 61 | +19 | Wiz Khalifa - Make It Hot | 2 | 61 | 0.029 | 7/28/08 |
| 62 | -7 | Train - Hey, Soul Sister | 205 | 14 | 1.103 | 8/7/09 |
| 63 | -11 | Victorious Cast - Freak the Freak Out (feat. Victoria J... | 39 | 13 | 0.189 | 11/22/10 |
| 64 | = | Michael Jackson - Hold My Hand (Duet with Akon) | 23 | 21 | 0.112 | 12/14/10 |
| 65 | +2 | Birdman & Lil Wayne - Fire Flame (feat. Lil Wayne) | 36 | 54 | 0.129 | 11/22/10 |
| 66 | +3 | Enrique Iglesias - Tonight (I'm F**kin' You) [feat. Lud... | 45 | 13 | 0.280 | 1/11/11 |
| 67 | -4 | Nicki Minaj - Right Thru Me | 42 | 34 | 0.174 | 11/22/10 |
| 68 | -6 | The Black Eyed Peas - I Gotta Feeling | 214 | 31 | 0.786 | 6/9/09 |
| 69 | -12 | Katy Perry - Teenage Dream | 167 | 1(16) | 2.516 | 7/23/10 |
| 70 | -9 | Eminem - Not Afraid | 205 | 5 | 1.749 | 6/21/10 |
| 71 | -11 | Mike Posner - Cooler Than Me (Single Mix) | 193 | 4 | 2.146 | 4/19/10 |
| 72 | -2 | Enrique Iglesias - I Like It (feat. Pitbull) | 217 | 3 | 2.414 | 5/3/10 |
| 73 | -5 | Bruno Mars - Marry You | 47 | 37 | 0.181 | 10/5/10 |
| 74 | +2 | Troop 41 - Do the John Wall | 17 | 67 | 0.052 | 11/19/10 |
| 75 | = | T.I. - That's All She Wrote (feat. Eminem) | 31 | 4 | 0.269 | 12/7/10 |
| 76 | +3 | Rick Ross - Aston Martin Music (feat. Drake & Chrisette... | 83 | 32 | 0.331 | 7/20/10 |
| 77 | +5 | Billy Currington - Let Me Down Easy | 20 | 72 | 0.159 | 9/21/10 |
| 78 | -5 | Ke$ha - Tik Tok | 128 | 28 | 0.658 | 1/4/09 |
| 79 | -8 | Katy Perry - Teenage Dream | 37 | 16 | 0.327 | 8/24/10 |
| 80 | -8 | Ke$ha - Take It Off | 162 | 6 | 1.385 | 1/4/09 |
| 81 | -3 | Cali Swag District - Teach Me How to Dougie | 22 | 56 | 0.091 | 4/6/10 |
| 82 | +1 | Cee Lo Green - Forget You | 62 | 17 | 0.317 | 9/14/10 |
| 83 | -2 | Linkin Park - Waiting for the End | 25 | 63 | 0.243 | 9/14/10 |
| 84 | -7 | P!nk - Raise Your Glass | 73 | 39 | 0.282 | 10/6/10 |
| 85 | -1 | Lady Antebellum - Need You Now | 87 | 38 | 0.390 | 1/26/10 |
| 86 | +27 | Rock Mafia - The Big Bang | 1 | 86 | 0.041 | 10/29/10 |
| 87 | +40 | Taio Cruz & Ludacris - Break Your Heart | 1 | 87 | 0.005 | 12/21/10 |
| 88 | -14 | Maroon 5 - Misery | 64 | 13 | 0.337 | 9/21/10 |
| 89 | -4 | Zac Brown Band - As She's Walking Away (feat. Alan Jack... | 105 | 29 | 0.393 | 9/20/10 |
| 90 | -3 | Wiz Khalifa - Black and Yellow | 13 | 80 | 0.039 | 12/21/10 |
| 91 | -2 | Sara Evans - A Little Bit Stronger | 24 | 48 | 0.251 | 9/14/10 |
| 92 | -6 | B.o.B - Airplanes (feat. Hayley Williams) | 167 | 2 | 1.925 | 4/13/10 |
| 93 | +4 | Jerrod Niemann - What Do You Want | 2 | 93 | 0.150 | 7/13/10 |
| 94 | -6 | Jason Derülo - Ridin' Solo | 175 | 4 | 1.774 | 2/26/10 |
| 95 | -5 | Chris Brown - Deuces (feat. Tyga & Kevin McCall) | 166 | 31 | 0.701 | 6/29/10 |
| 96 | -5 | Taio Cruz - Imagine | 2 | 91 | 0.006 | 12/28/10 |
| 97 | +6 | Lupe Fiasco - The Show Goes On | 18 | 18 | 0.160 | 10/25/10 |
| 98 | +31 | Coolio - Gangsta's Paradise | 1 | 98 | 0.047 | 3/15/05 |
| 99 | -5 | Kanye West & Pusha T - Runaway | 35 | 52 | 0.133 | 11/22/10 |
| 100 | +9 | Antoine Dodson & The Gregory Brothers - Bed Intruder So... | 79 | 29 | 0.408 | 8/10/10 |
| 102 | -4 | Eric Church - Smoke a Little Smoke | 71 | 55 | 0.342 | 3/24/09 |
| 103 | -11 | Big Time Rush - Big Night | 7 | 55 | 0.053 | 10/11/10 |
| 104 | -9 | Justin Bieber & Ludacris - Baby | 139 | 27 | 0.676 | 3/23/10 |
| 116 | -17 | Usher - OMG (feat. will.i.am) | 169 | 2 | 1.720 | 3/30/10 |
| 118 | -22 | La Roux - Bulletproof | 133 | 9 | 0.998 | 9/22/09 |
| 132 | +66 | Gerry Rafferty - Right Down the Line | -- | 132 | 0.003 | 12/31/77 |
| 149 | +76 | P!nk - F**kin' Perfect | 5 | 66 | 0.037 | 11/16/10 |
| 152 | +44 | Fabolous - You Be Killin Em | -- | 152 | 0.052 | 8/31/10 |
| 159 | +46 | Edward Sharpe & The Magnetic Zeros - Home | 6 | 71 | 0.211 | 7/27/10 |
| 170 | +31 | Taio Cruz - Dynamite (iTunes Session) | -- | 170 | 0.003 | 1/4/11 |
| 178 | +11 | Sunny Sweeney - From a Table Away | -- | 178 | 0.081 | 6/29/10 |
| 185 | +26 | Travis Porter - Make It Rain | -- | 185 | 0.022 | 12/2/10 |
| 190 | +58 | P!nk - F**kin' Perfect | 8 | 44 | 0.046 | 12/14/10 |
| 239 | +78 | Leighton Meester - Summer Girl | -- | 239 | 0.004 | 12/21/10 |
| 259 | +98 | Sean Kingston - Party All Night (Sleep All Day) | 3 | 53 | 0.024 | 12/21/10 |
| 269 | +293 | Jeff Buckley - Hallelujah | -- | 112 | 0.128 | 8/9/94 |
| 340 | +164 | Fefe Dobson - Stuttering | -- | 340 | 0.016 | 11/30/10 |
| 424 | +117 | Taio Cruz - Higher | -- | 424 | 0.001 | 12/21/10 |
| 448 | +315 | Stealers Wheel - Stuck In the Middle With You | -- | 448 | 0.001 | 4/28/09 |
| 465 | +321 | Kenny Chesney - The Boys of Fall | 20 | 49 | 0.090 | 9/28/10 |
| 568 | +181 | Randy Montana - 1,000 Faces | -- | 568 | 0.001 | 1/4/11 |
| 605 | +197 | Timbaland - Carry Out (feat. Justin Timberlake) | 19 | 62 | 0.191 | 12/8/09 |
| 609 | +184 | Joe Nichols - Shape I'm In | -- | 433 | 0.022 | 8/10/10 |
| 627 | NEW | Leona Lewis - Happy | -- | 627 | 0.000 | 11/17/09 |
| 714 | +221 | Rascal Flatts - I Won't Let Go | -- | 284 | 0.008 | 11/16/10 |
| 745 | +198 | Leighton Meester - Words I Couldn't Say | -- | 664 | 0.003 | 10/26/10 |
