Kworb posted some sales predictions in the iTunes thread, I'll use those predictions & current overall AI to give an idea of what the Hot 100 may look like.
This is not accurate, sales & airplay will be different on Wednesday The sales predictions are also not official, sales may end up being quite different, we don't know.
1. Rihanna - S&M (featuring Britney Spears) 308 + 130 = 438
2. Katy Perry - E.T. (featuring Kanye West) 295 + 126 = 421
3. The Black Eyed Peas - Just Can't Get Enough 181 + 67 = 248
4. Jeremih - Down On Me (featuring 50 Cent) 137 + 95 = 232
5. Adele - Rolling In the Deep 158 + 55 = 213 (

)
6. Cee Lo Green - Forget You 103 + 107 = 210
7. Chris Brown - Look At Me Now (featuring Busta Rhymes & Lil Wayne) 130 + 73 = 203
8. Britney Spears - Till the World Ends 128 + 61 = 189
9. Jennifer Lopez - On the Floor (featuring Pitbull) 132 + 54 = 186
10. Bruno Mars - The Lazy Song 125 + 40 = 165
Judas could be in the #13-14 area (depending on where FP charts).