I still think Zelda U will be revealed at E3 a la some other Zelda titles, but it would be nice to see. They are limiting it to releases from now till the end of summer for the 3DS and Wii U, no NX Or mobile news.
We will probably get 1 big 3DS game and 1 big Wii u Game announcement
Probably Pikmin 4 and I can't think of a 3DS one
My real hopes:
- Some type of Moon/Sun news
- Animal Crossing Wii U

- Star Fox Multiplayer
- Splatoon DLC
- More cool Amiibo please
- A cool exclusive new 3ds title or some game that utilizes it better
- Mario Galaxy 3