How about just make a damn great album, so you won't have to worry about flopping?
And in that case any single choice won't matter because the entire album is strong
But to answer the question, I think the idea of artists these days releasing singles that appeal to pop and urban is a great idea.
For example, Beyonce released IIWAB and SL, and had a massive first week sales
And so did Rihanna with OG and WMN?, and she pulled her strongest weekly sales yet