I know exactly what you're going through. I went into high school as well virtually knowing anyone, and I graduated this year with some of the best friends you could ask for. However now I have the exact same problem going to college, only this time I'll be away from home.
I know this sounds beyond cliche, but just be yourself. Perhaps you could join some sort of club or just try to talk to people in classes and at lunch etc. You're bound to find at least one person who has similar interests to you. Just remember one good friend is better than 20 bad ones.
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