Like the original series, the show is set in the same house in San Francisco, California. Recently widowed D.J. Tanner-Fuller is a veterinarian and the mother of three young boys. After the sudden death of her husband, Tommy, who was following his hazardous duties as a firefighter, D.J. accepts the help of her sister Stephanie and best friend Kimmy to move in and take part in raising her three sons, 13-year-old Jackson, 7-year-old Max, and baby Tommy Jr. Kimmy's teenage daughter Ramona also moves in.
press release from Netflix gives a plot synopsis."In 'Fuller House,' the adventures that began in 1987 on 'Full House' continue, with veterinarian D.J. Tanner-Fuller pregnant and recently widowed, living in San Francisco," it reads. "D.J.'s younger sister/aspiring musician Stephanie Tanner and D.J.'s lifelong best friend/fellow single mother Kimmy Gibbler, along with Kimmy's feisty teenage daughter Ramona, all move in to help take care of D.J.'s two boys -- the rebellious 12-year-old J.D. and neurotic 7-year-old Max -- and her soon-to-arrive baby."
Yas, sounds like Full House but with female leads.